Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling.
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| Title: | Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling. |
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| Authors: | Wierbiłowicz K; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA.; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Yang CS; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA., Almaghasilah A; Department of Molecular and Biomedical Sciences, University of Maine, Orono, ME, USA., Wesołowski PA; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Pracht P; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Dworak NM; Advanced Microscopy Facility, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Masur J; University of Virginia Comprehensive Cancer Center, Charlottesville, VA, 22903, USA., Wijngaarden S; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden, 2333 CC, The Netherlands., Filippov DV; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden, 2333 CC, The Netherlands., Wales DJ; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Kelley JB; Department of Molecular and Biomedical Sciences, University of Maine, Orono, ME, USA., Ratan A; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA.; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Paschal BM; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA. paschal@virginia.edu. |
| Source: | The EMBO journal [EMBO J] 2025 Sep; Vol. 44 (17), pp. 4720-4744. Date of Electronic Publication: 2025 Jul 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-025-00510-4 |
