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Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling.

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Title: Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling.
Authors: Wierbiłowicz K; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA.; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Yang CS; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA., Almaghasilah A; Department of Molecular and Biomedical Sciences, University of Maine, Orono, ME, USA., Wesołowski PA; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Pracht P; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Dworak NM; Advanced Microscopy Facility, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Masur J; University of Virginia Comprehensive Cancer Center, Charlottesville, VA, 22903, USA., Wijngaarden S; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden, 2333 CC, The Netherlands., Filippov DV; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden, 2333 CC, The Netherlands., Wales DJ; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK., Kelley JB; Department of Molecular and Biomedical Sciences, University of Maine, Orono, ME, USA., Ratan A; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA.; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Paschal BM; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA. paschal@virginia.edu.
Source: The EMBO journal [EMBO J] 2025 Sep; Vol. 44 (17), pp. 4720-4744. Date of Electronic Publication: 2025 Jul 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling.
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  Data: <searchLink fieldCode="AU" term="%22Wierbiłowicz+K%22">Wierbiłowicz K</searchLink>; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA.; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Yang+CS%22">Yang CS</searchLink>; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA.<br /><searchLink fieldCode="AU" term="%22Almaghasilah+A%22">Almaghasilah A</searchLink>; Department of Molecular and Biomedical Sciences, University of Maine, Orono, ME, USA.<br /><searchLink fieldCode="AU" term="%22Wesołowski+PA%22">Wesołowski PA</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.<br /><searchLink fieldCode="AU" term="%22Pracht+P%22">Pracht P</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.<br /><searchLink fieldCode="AU" term="%22Dworak+NM%22">Dworak NM</searchLink>; Advanced Microscopy Facility, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA.<br /><searchLink fieldCode="AU" term="%22Masur+J%22">Masur J</searchLink>; University of Virginia Comprehensive Cancer Center, Charlottesville, VA, 22903, USA.<br /><searchLink fieldCode="AU" term="%22Wijngaarden+S%22">Wijngaarden S</searchLink>; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden, 2333 CC, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Filippov+DV%22">Filippov DV</searchLink>; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden, 2333 CC, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wales+DJ%22">Wales DJ</searchLink>; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.<br /><searchLink fieldCode="AU" term="%22Kelley+JB%22">Kelley JB</searchLink>; Department of Molecular and Biomedical Sciences, University of Maine, Orono, ME, USA.<br /><searchLink fieldCode="AU" term="%22Ratan+A%22">Ratan A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA.; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Paschal+BM%22">Paschal BM</searchLink>; Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, PO Box 800733, Charlottesville, VA, 22908, USA. paschal@virginia.edu.
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