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Phase 1 study of ABI-009 (nab-rapamycin) for surgically refractory epilepsy (RaSuRE).

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Title: Phase 1 study of ABI-009 (nab-rapamycin) for surgically refractory epilepsy (RaSuRE).
Authors: Hall K; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Saneto R; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Randle S; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Wainwright MS; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Berry P; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Leary S; Cancer and Blood Disorders Center, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Mirzaa G; Department of Genetic Medicine, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Lockrow J; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Goldstein H; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Ojemann J; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Thiessen R; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Willis H; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Sullivan E; Biostats, Epidemiology, and Analytics in Research Core, Seattle Children's Hospital, Seattle, Washington, USA., Rivers R; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Klein J; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Hauptman JS; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.; Division of Neurosurgery, Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, Arizona, USA.
Source: Epilepsia [Epilepsia] 2025 Nov; Vol. 66 (11), pp. 4246-4258. Date of Electronic Publication: 2025 Jul 19.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase 1 study of ABI-009 (nab-rapamycin) for surgically refractory epilepsy (RaSuRE).
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  Data: <searchLink fieldCode="AU" term="%22Hall+K%22">Hall K</searchLink>; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Saneto+R%22">Saneto R</searchLink>; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Randle+S%22">Randle S</searchLink>; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Wainwright+MS%22">Wainwright MS</searchLink>; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Berry+P%22">Berry P</searchLink>; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Leary+S%22">Leary S</searchLink>; Cancer and Blood Disorders Center, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Mirzaa+G%22">Mirzaa G</searchLink>; Department of Genetic Medicine, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Lockrow+J%22">Lockrow J</searchLink>; Department of Neurology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Goldstein+H%22">Goldstein H</searchLink>; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Ojemann+J%22">Ojemann J</searchLink>; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Thiessen+R%22">Thiessen R</searchLink>; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Willis+H%22">Willis H</searchLink>; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Sullivan+E%22">Sullivan E</searchLink>; Biostats, Epidemiology, and Analytics in Research Core, Seattle Children's Hospital, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Rivers+R%22">Rivers R</searchLink>; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Klein+J%22">Klein J</searchLink>; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Hauptman+JS%22">Hauptman JS</searchLink>; Division of Neurosurgery, Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.; Division of Neurosurgery, Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, Arizona, USA.
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  Data: <searchLink fieldCode="JN" term="%222983306R%22">Epilepsia</searchLink> [Epilepsia] 2025 Nov; Vol. 66 (11), pp. 4246-4258. <i>Date of Electronic Publication: </i>2025 Jul 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Blackwell+Science%22">Blackwell Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2983306R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-1167 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200139580%22">00139580 </searchLink><i>NLM ISO Abbreviation: </i>Epilepsia <i>Subsets: </i>MEDLINE
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        Value: 10.1111/epi.18555
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              Text: 2025 Nov
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