Hesperidin loaded bilosomes mitigate the nephrotoxicity induced by methotrexate; biochemical and molecular in vivo investigations.

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Title: Hesperidin loaded bilosomes mitigate the nephrotoxicity induced by methotrexate; biochemical and molecular in vivo investigations.
Authors: Mahmoud SH; Biotechnology and Life Sciences Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University, Beni-Suef, 62511, Egypt. Shiemaa200941@gmail.com., Moselhy WA; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt., Azmy AF; Department of Microbiology and Immunology, Faculty of Pharmacy, Beni- Suef University, Beni-Suef, 62511, Egypt., El-Ela FIA; Pharmacology Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, 62511, Egypt.
Source: BMC nephrology [BMC Nephrol] 2025 Jul 21; Vol. 26 (1), pp. 404. Date of Electronic Publication: 2025 Jul 21.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967793 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2369 (Electronic) Linking ISSN: 14712369 NLM ISO Abbreviation: BMC Nephrol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1471-2369
DOI:10.1186/s12882-025-04328-4