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Integrating pulmonary and systemic transcriptomes to characterize lung injury after pediatric hematopoietic stem cell transplant.

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Title: Integrating pulmonary and systemic transcriptomes to characterize lung injury after pediatric hematopoietic stem cell transplant.
Authors: Pearce EM; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA., Evans E; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA., Mayday MY; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.; Departments of Laboratory Medicine and Pathology, Yale School of Medicine, New Haven, Connecticut, USA., Reyes G; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA., Simon MR; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA., Blum J; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA., Kim H; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA., Mu J; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA., Shaw PJ; The Children's Hospital at Westmead, Westmead, New South Wales, Australia.; Pediatric Transplantation and Cell Therapy Consortium., Rowan CM; Pediatric Transplantation and Cell Therapy Consortium.; Indiana University, Department of Pediatrics, Division of Critical Care Medicine, Indianapolis, Indiana, USA., Auletta JJ; Pediatric Transplantation and Cell Therapy Consortium.; Hematology/Oncology/BMT and Infectious Diseases, Nationwide Children's Hospital, Columbus, Ohio, USA.; Center for International Blood and Marrow Transplant Research (CIBMTR), National Marrow Donor Program/Be The Match, Minneapolis, Minnesota, USA., Martin PL; Pediatric Transplantation and Cell Therapy Consortium.; Division of Pediatric and Cellular Therapy, Duke University Medical Center, Durham, North Carolina, USA., Hurley C; Pediatric Transplantation and Cell Therapy Consortium.; Division of Critical Care, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Kreml EM; Pediatric Transplantation and Cell Therapy Consortium.; Department of Child Health, Division of Critical Care Medicine, University of Arizona, Phoenix, Arizona, USA., Qayed M; Pediatric Transplantation and Cell Therapy Consortium.; Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta and Emory University, Atlanta, Georgia, USA., Abdel-Azim H; Pediatric Transplantation and Cell Therapy Consortium.; Department of Pediatrics, Division of Hematology/Oncology and Transplant and Cell Therapy, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Loma Linda University School of Medicine, Cancer Center, Children Hospital and Medical Center, Loma Linda, California, USA., Keating AK; Pediatric Transplantation and Cell Therapy Consortium.; Harvard Medical School, Division of Pediatric Oncology, Department of Pediatrics, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts, USA.; Center for Cancer and Blood Disorders, Children's Hospital Colorado and University of Colorado, Aurora, Colorado, USA., Cuvelier G; Pediatric Transplantation and Cell Therapy Consortium.; CancerCare Manitoba, Manitoba Blood and Marrow Transplant Program, University of Manitoba, Winnipeg, Manitoba, Canada., Hume JR; Pediatric Transplantation and Cell Therapy Consortium.; University of Minnesota, Department of Pediatrics, Division of Critical Care Medicine, Minneapolis, Minnesota, USA., Killinger JS; Pediatric Transplantation and Cell Therapy Consortium.; Division of Pediatric Critical Care, Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., Godder K; Pediatric Transplantation and Cell Therapy Consortium.; Cancer and Blood Disorders Center, Nicklaus Children's Hospital, Miami, Florida, USA., Hanna R; Pediatric Transplantation and Cell Therapy Consortium.; Department of Pediatric Hematology, Oncology and Blood and Marrow Transplantation, Pediatric Institute, Cleveland Clinic, Cleveland, Ohio, USA., Duncan CN; Pediatric Transplantation and Cell Therapy Consortium.; Harvard Medical School, Division of Pediatric Oncology, Department of Pediatrics, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts, USA., Quigg TC; Pediatric Transplantation and Cell Therapy Consortium.; Pediatric Blood and Marrow Transplantation Program, Texas Transplant Institute, Methodist Children's Hospital, San Antonio, Texas, USA.; Section of Pediatric BMT and Cellular Therapy, Helen DeVos Children's Hospital, Grand Rapids, Michigan, USA., Castillo P; Pediatric Transplantation and Cell Therapy Consortium.; University of Florida, Gainesville, UF Health Shands Children's Hospital, Gainesville, Florida, USA., Lalefar NR; Pediatric Transplantation and Cell Therapy Consortium.; Division of Pediatric Hematology/Oncology, UCSF Benioff Children's Hospital Oakland, University of California San Francisco, Oakland, California, USA., Fitzgerald JC; Pediatric Transplantation and Cell Therapy Consortium.; Department of Anesthesiology and Critical Care, Perelman School of Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Mahadeo KM; Pediatric Transplantation and Cell Therapy Consortium.; Division of Pediatric and Cellular Therapy, Duke University Medical Center, Durham, North Carolina, USA.; Department of Pediatrics, Division of Hematology/Oncology, MD Anderson Cancer Center, Houston, Texas, USA., Satwani P; Pediatric Transplantation and Cell Therapy Consortium.; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics, Columbia University, New York, New York, USA., Moore TB; Pediatric Transplantation and Cell Therapy Consortium.; Department of Pediatric Hematology-Oncology, Mattel Children's Hospital, University of California, Los Angeles, California, USA., Hanisch B; Pediatric Transplantation and Cell Therapy Consortium.; Children's National Hospital, Washington DC, USA., Abdel-Mageed A; Pediatric Transplantation and Cell Therapy Consortium.; Section of Pediatric BMT and Cellular Therapy, Helen DeVos Children's Hospital, Grand Rapids, Michigan, USA., Davis DB; Pediatric Transplantation and Cell Therapy Consortium.; Department of Pediatrics, Hematology/Oncology, University of Mississippi Medical Center, Jackson, Mississippi, USA., Hudspeth MP; Pediatric Transplantation and Cell Therapy Consortium.; Adult and Pediatric Blood & Marrow Transplantation, Pediatric Hematology/Oncology, Medical University of South Carolina Children's Hospital/Hollings Cancer Center, Charleston, South Carolina, USA., Yanik GA; Pediatric Transplantation and Cell Therapy Consortium.; Pediatric Blood and Bone Marrow Transplantation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA., Pulsipher MA; Pediatric Transplantation and Cell Therapy Consortium.; Division of Pediatric Hematology and Oncology, Intermountain Primary Children's Hospital, Huntsman Cancer Institute, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, Utah, USA., Dvorak CC; Pediatric Transplantation and Cell Therapy Consortium.; Division of Allergy, Immunology, and Bone Marrow Transplantation, Department of Pediatrics, and., DeRisi JL; Department of Biochemistry and Biophysics, UCSF, San Francisco, California, USA.; Chan Zuckerberg Biohub, San Francisco, California, USA., Zinter MS; Division of Critical Care Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.; Pediatric Transplantation and Cell Therapy Consortium.; Division of Allergy, Immunology, and Bone Marrow Transplantation, Department of Pediatrics, and.
Source: JCI insight [JCI Insight] 2025 Jul 22; Vol. 10 (17). Date of Electronic Publication: 2025 Jul 22 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
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  Data: Integrating pulmonary and systemic transcriptomes to characterize lung injury after pediatric hematopoietic stem cell transplant.
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Pediatric Transplantation and Cell Therapy Consortium.; University of Florida, Gainesville, UF Health Shands Children's Hospital, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Lalefar+NR%22">Lalefar NR</searchLink>; Pediatric Transplantation and Cell Therapy Consortium.; Division of Pediatric Hematology/Oncology, UCSF Benioff Children's Hospital Oakland, University of California San Francisco, Oakland, California, USA.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+JC%22">Fitzgerald JC</searchLink>; Pediatric Transplantation and Cell Therapy Consortium.; Department of Anesthesiology and Critical Care, Perelman School of Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Mahadeo+KM%22">Mahadeo KM</searchLink>; Pediatric Transplantation and Cell Therapy Consortium.; Division of Pediatric and Cellular Therapy, Duke University Medical Center, Durham, North Carolina, USA.; 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