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Dexmedetomidine and alfaxalone intravenous co-administration for the induction of general anaesthesia in bitches undergoing C-section: impact on newborn viability and pharmacokinetics.

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Title: Dexmedetomidine and alfaxalone intravenous co-administration for the induction of general anaesthesia in bitches undergoing C-section: impact on newborn viability and pharmacokinetics.
Authors: Di Cesare F; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy., Brioschi FA; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy. Electronic address: federica.brioschi@guest.unimi.it., Ravasio G; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy., Groppetti D; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy., Amari M; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy., Giussani E; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy., Draghi S; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy. Electronic address: susanna.draghi@unimi.it., Sala G; Department of Veterinary Sciences, University of Pisa, Via Livornese (SP-22), San Piero a Grado, Pisa, 56124, Italy., Pecile A; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy., Cagnardi P; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell'Università 6, 26900, Lodi, Italy.
Source: Theriogenology [Theriogenology] 2025 Nov; Vol. 247, pp. 117578. Date of Electronic Publication: 2025 Jul 14.
Publication Type: Journal Article; Clinical Trial, Veterinary
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0421510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3231 (Electronic) Linking ISSN: 0093691X NLM ISO Abbreviation: Theriogenology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-3231
DOI:10.1016/j.theriogenology.2025.117578