What guides regional nodal irradiation in node positive breast cancer following upfront sentinel lymph node biopsy?

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Title: What guides regional nodal irradiation in node positive breast cancer following upfront sentinel lymph node biopsy?
Authors: Putora PM; HOCH, Cantonal Hospital St.Gallen, Department of Radiation Oncology, St. Gallen, Switzerland; Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, Switzerland. Electronic address: qsiamfiby@mozmail.com., Henke G; Department of Radiation Oncology, Team Radiologie Plus, Cantonal Hospital Münsterlingen, Münsterlingen, Switzerland., Beşe N; MAA Acibadem University, Research Institute of Senology, Istanbul Turkey., Boersma L; Department of Radiation Oncology (Maastro), GROW Research Institute for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, the Netherlands., Coles CE; Department of Oncology, University of Cambridge, Cambridge, UK., de Boniface J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Surgery, Capio St. Göran's Hospital, Stockholm, Sweden., Duane F; St Luke's Radiation Oncology Network, Dublin, Ireland; Trinity St James's Cancer Institute, Dublin, Ireland., Gabryś D; Department of Radiation Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland., Jagsi R; Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA., Kim K; Department of Radiation Oncology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, Republic of Korea., Kirby AM; Department of Radiotherapy, Royal Marsden NHS Foundation Trust & Institute of Cancer Research, Sutton, UK., Marta GN; Department of Radiation Oncology, Hospital Sírio-Libanês, São Paulo, Brazil; Latin America Cooperative Oncology Group, Porto Alegre, Brazil; Postgraduate Program, Department of Radiology and Oncology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Meattini I; Department of Experimental and Clinical Biomedical Sciences 'M. Serio', University of Florence, Florence, Italy; Radiation Oncology & Breast Unit, Azienda Ospedaliero Universitaria Careggi, Florence, Italy., Mjaaland I; Department of Oncology and Hematology, Stavanger University Hospital, Stavanger, Norway., Montero A; Department of Radiation Oncology, HM Hospitales, Madrid, Spain; Camilo José Cela University, Faculty of Health, Madrid, Spain., Offersen BV; Department of Experimental Clinical Oncology, Department of Oncology, Danish Centre for Particle Therapy, Aarhus University Hospital, University of Aarhus, Denmark., Ramiah D; Division of Radiation Oncology, University of the Witwatersrand, Johannesburg, South Africa., Ratoša I; Division of Radiation Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Strnad V; Department of Radiation Oncology, University Hospital, Friedrich-Alexander-Universität Erlangen-Nuernberg Erlangen, Comprehensive Cancer Center Erlangen-EMN Erlangen, Germany., Zeidan YH; Lynn Cancer Institute, Baptist Health South Florida, Boca Raton, Florida, USA., Poortmans P; University of Antwerp, Faculty of Medicine and Health Sciences, Wilrijk-Antwerp, Belgium; Department of Radiation Oncology, Iridium Netwerk, Wilrijk-Antwerp, Belgium., Kaidar-Person O; Breast Radiation Unit, Sheba Medical Center, Ramat Gan, Israel; Tel Aviv University, Tel Aviv, Israel.
Source: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2025 Oct; Vol. 211, pp. 111055. Date of Electronic Publication: 2025 Jul 20.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Putora+PM%22">Putora PM</searchLink>; HOCH, Cantonal Hospital St.Gallen, Department of Radiation Oncology, St. Gallen, Switzerland; Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, Switzerland. Electronic address: qsiamfiby@mozmail.com.<br /><searchLink fieldCode="AU" term="%22Henke+G%22">Henke G</searchLink>; Department of Radiation Oncology, Team Radiologie Plus, Cantonal Hospital Münsterlingen, Münsterlingen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Beşe+N%22">Beşe N</searchLink>; MAA Acibadem University, Research Institute of Senology, Istanbul Turkey.<br /><searchLink fieldCode="AU" term="%22Boersma+L%22">Boersma L</searchLink>; Department of Radiation Oncology (Maastro), GROW Research Institute for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Coles+CE%22">Coles CE</searchLink>; Department of Oncology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22de+Boniface+J%22">de Boniface J</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Surgery, Capio St. Göran's Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Duane+F%22">Duane F</searchLink>; St Luke's Radiation Oncology Network, Dublin, Ireland; Trinity St James's Cancer Institute, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Gabryś+D%22">Gabryś D</searchLink>; Department of Radiation Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland.<br /><searchLink fieldCode="AU" term="%22Jagsi+R%22">Jagsi R</searchLink>; Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+K%22">Kim K</searchLink>; Department of Radiation Oncology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; Department of Radiation Oncology, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kirby+AM%22">Kirby AM</searchLink>; Department of Radiotherapy, Royal Marsden NHS Foundation Trust & Institute of Cancer Research, Sutton, UK.<br /><searchLink fieldCode="AU" term="%22Marta+GN%22">Marta GN</searchLink>; Department of Radiation Oncology, Hospital Sírio-Libanês, São Paulo, Brazil; Latin America Cooperative Oncology Group, Porto Alegre, Brazil; Postgraduate Program, Department of Radiology and Oncology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Meattini+I%22">Meattini I</searchLink>; Department of Experimental and Clinical Biomedical Sciences 'M. Serio', University of Florence, Florence, Italy; Radiation Oncology & Breast Unit, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Mjaaland+I%22">Mjaaland I</searchLink>; Department of Oncology and Hematology, Stavanger University Hospital, Stavanger, Norway.<br /><searchLink fieldCode="AU" term="%22Montero+A%22">Montero A</searchLink>; Department of Radiation Oncology, HM Hospitales, Madrid, Spain; Camilo José Cela University, Faculty of Health, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Offersen+BV%22">Offersen BV</searchLink>; Department of Experimental Clinical Oncology, Department of Oncology, Danish Centre for Particle Therapy, Aarhus University Hospital, University of Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Ramiah+D%22">Ramiah D</searchLink>; Division of Radiation Oncology, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Ratoša+I%22">Ratoša I</searchLink>; Division of Radiation Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.<br /><searchLink fieldCode="AU" term="%22Strnad+V%22">Strnad V</searchLink>; Department of Radiation Oncology, University Hospital, Friedrich-Alexander-Universität Erlangen-Nuernberg Erlangen, Comprehensive Cancer Center Erlangen-EMN Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Zeidan+YH%22">Zeidan YH</searchLink>; Lynn Cancer Institute, Baptist Health South Florida, Boca Raton, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Poortmans+P%22">Poortmans P</searchLink>; University of Antwerp, Faculty of Medicine and Health Sciences, Wilrijk-Antwerp, Belgium; Department of Radiation Oncology, Iridium Netwerk, Wilrijk-Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Kaidar-Person+O%22">Kaidar-Person O</searchLink>; Breast Radiation Unit, Sheba Medical Center, Ramat Gan, Israel; Tel Aviv University, Tel Aviv, Israel.
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