Transcriptomic analyses of peripheral blood mononuclear cells reveal age-specific basal and acute exercise responsiveness differences in humans.

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Title: Transcriptomic analyses of peripheral blood mononuclear cells reveal age-specific basal and acute exercise responsiveness differences in humans.
Authors: Ruple BA; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department VA Medical Center, Salt Lake City, Utah, United States.; Division of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States., Carlini NA; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department VA Medical Center, Salt Lake City, Utah, United States.; Division of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States., Kofoed JS; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, United States., Rostamkhani H; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, United States., Hanson BE; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department VA Medical Center, Salt Lake City, Utah, United States.; Division of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States., Wilcox I; Division of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States., Craig JC; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department VA Medical Center, Salt Lake City, Utah, United States.; Division of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States., Osburn SC; Department of Health and Exercise Science, Colorado State University, Fort Collins, Colorado, United States.; Center for Healthy Aging, Colorado State University, Fort Collins, Colorado, United States., Drummond MJ; Department of Physical Therapy and Athletic Training, University of Utah, Salt Lake City, Utah, United States., Broxterman RM; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department VA Medical Center, Salt Lake City, Utah, United States.; Division of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States.; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, United States., Trinity JD; Geriatric Research, Education, and Clinical Center, George E. Wahlen Department VA Medical Center, Salt Lake City, Utah, United States.; Division of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States.; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah, United States.
Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2025 Aug 01; Vol. 329 (2), pp. E381-E390. Date of Electronic Publication: 2025 Jul 22.
Publication Type: Journal Article
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1555 (Electronic) Linking ISSN: 01931849 NLM ISO Abbreviation: Am J Physiol Endocrinol Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1522-1555
DOI:10.1152/ajpendo.00169.2025