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Specific oncogene activation of the cell of origin in mucosal melanoma.

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Title: Specific oncogene activation of the cell of origin in mucosal melanoma.
Authors: Babu S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Chen J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Baron CS; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA., Sun K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Robitschek E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., McConnell AM; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA., Wu C; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA., Dedeilia A; Massachusetts General Hospital (MGH) Department of Surgery, MGH Krantz Center for Cancer Research, Boston, MA, USA., Sade-Feldman M; Massachusetts General Hospital (MGH) Department of Surgery, MGH Krantz Center for Cancer Research, Boston, MA, USA., Modhurima R; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA., Manos MP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Chen KY; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA., Cox AM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Ludwig CG; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA., Kellis M; Broad Institute of Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Buchbinder EI; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Hacohen N; Massachusetts General Hospital (MGH) Department of Surgery, MGH Krantz Center for Cancer Research, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Immunology, Harvard Medical School, Boston, MA, USA., Yang J; Broad Institute of Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Boland GM; Massachusetts General Hospital (MGH) Department of Surgery, MGH Krantz Center for Cancer Research, Boston, MA, USA., Abraham BJ; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Liu D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Zon LI; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA. leonard.zon@enders.tch.harvard.edu., Insco ML; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Megan_Insco@dfci.harvard.edu.
Source: Nature communications [Nat Commun] 2025 Jul 22; Vol. 16 (1), pp. 6750. Date of Electronic Publication: 2025 Jul 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Specific oncogene activation of the cell of origin in mucosal melanoma.
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  Data: <searchLink fieldCode="AU" term="%22Babu+S%22">Babu S</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Baron+CS%22">Baron CS</searchLink>; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sun+K%22">Sun K</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Robitschek+E%22">Robitschek E</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McConnell+AM%22">McConnell AM</searchLink>; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+C%22">Wu C</searchLink>; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dedeilia+A%22">Dedeilia A</searchLink>; Massachusetts General Hospital (MGH) Department of Surgery, MGH Krantz Center for Cancer Research, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sade-Feldman+M%22">Sade-Feldman M</searchLink>; Massachusetts General Hospital (MGH) Department of Surgery, MGH Krantz Center for Cancer Research, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Modhurima+R%22">Modhurima R</searchLink>; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Manos+MP%22">Manos MP</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+KY%22">Chen KY</searchLink>; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cox+AM%22">Cox AM</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ludwig+CG%22">Ludwig CG</searchLink>; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kellis+M%22">Kellis M</searchLink>; Broad Institute of Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Buchbinder+EI%22">Buchbinder EI</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hacohen+N%22">Hacohen N</searchLink>; Massachusetts General Hospital (MGH) Department of Surgery, MGH Krantz Center for Cancer Research, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Department of Immunology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Broad Institute of Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Boland+GM%22">Boland GM</searchLink>; Massachusetts General Hospital (MGH) Department of Surgery, MGH Krantz Center for Cancer Research, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Abraham+BJ%22">Abraham BJ</searchLink>; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zon+LI%22">Zon LI</searchLink>; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Howard Hughes Medical Institute, Boston, MA, USA. leonard.zon@enders.tch.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Insco+ML%22">Insco ML</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Megan_Insco@dfci.harvard.edu.
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