Proteomic analysis reveals inhibition of mevalonate and glycolysis pathways in hepatocytes by 27-hydroxycholesterol.

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Title: Proteomic analysis reveals inhibition of mevalonate and glycolysis pathways in hepatocytes by 27-hydroxycholesterol.
Authors: Shim WS; Department of Convergence Medicine, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea., Lee S; Neurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu, 41062, Republic of Korea., Azamov B; Department of Convergence Medicine, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea., Lee C; Department of Convergence Medicine, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea., Kang Y; Department of Convergence Medicine, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea., Lee KM; Department of Life Science and Environmental Biochemistry, Pusan National University, Miryang, 50463, Republic of Korea., Hong C; Department of Anatomy, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.; Department of Convergence Medical Science, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea., Kwon SM; Laboratory for Vascular Medicine and Stem Cell Biology, Department of Physiology, Medical Research Institute, School of Medicine, Pusan National University, Yangsan, 50612, Republic of Korea., Kim K; Department of Pharmacology, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea., Lee D; Department of Convergence Medicine, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea., Yoon JH; Neurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu, 41062, Republic of Korea., Song P; Department of Convergence Medicine, Pusan National University School of Medicine, Yangsan, 50612, Republic of Korea.
Source: The Biochemical journal [Biochem J] 2025 Aug 04; Vol. 482 (15). Date of Electronic Publication: 2025 Aug 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Electronic Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1470-8728
DOI:10.1042/BCJ20253035