A STAT3/integrin axis accelerates pancreatic cancer initiation and progression.

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Title: A STAT3/integrin axis accelerates pancreatic cancer initiation and progression.
Authors: Campos AD; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Shepard RM; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Ortega Z; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Heumann I; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Wilke AE; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Nam A; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Cable C; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Kouhmareh K; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Klemke R; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Mattson NM; Division of Genomics and Precision Medicine, Department of Medicine, University of California San Diego, La Jolla, San Diego, CA, USA., Ideker T; Division of Genomics and Precision Medicine, Department of Medicine, University of California San Diego, La Jolla, San Diego, CA, USA; Departments of Bioengineering and Computer Science and Engineering, University of California San Diego, La Jolla, San Diego, CA, USA., De Arruda Saldanha C; School of Medicine, University of California San Diego, La Jolla, San Diego, CA, USA., Heinz S; School of Medicine, University of California San Diego, La Jolla, San Diego, CA, USA., Weaver V; Department of Surgery and Center for Bioengineering and Tissue Regeneration, University of California San Francisco, San Francisco, CA, USA., Von Schalscha T; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Wettersten HI; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Weis SM; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA., Cheresh DA; Department of Pathology, Moores Cancer Center at the University of California San Diego, La Jolla, San Diego, CA, USA; Department of Pathology, Sanford Consortium for Regenerative Medicine at the University of California San Diego, La Jolla, San Diego, CA, USA. Electronic address: dcheresh@health.ucsd.edu.
Source: Cell reports [Cell Rep] 2025 Aug 26; Vol. 44 (8), pp. 116010. Date of Electronic Publication: 2025 Jul 22.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2025.116010