A PEDF-Derived Short Peptide Prevents Sodium Iodate-Induced Retinal Degeneration in Rats by Activating the SLC7A11/GSH/GPX4 Pathway in the RPE Cells.

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Title: A PEDF-Derived Short Peptide Prevents Sodium Iodate-Induced Retinal Degeneration in Rats by Activating the SLC7A11/GSH/GPX4 Pathway in the RPE Cells.
Authors: Ho TC; Department of Medical Research, Mackay Memorial Hospital, New Taipei City, Taiwan., Tsai SH; Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.; Department of Optometry, Mackay Medical College, New Taipei City, Taiwan., Yeh SI; Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan., Sun MH; Department of Ophthalmology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Tsao YP; Department of Medical Research, Mackay Memorial Hospital, New Taipei City, Taiwan.; Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.
Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2025 Jul; Vol. 29 (14), pp. e70693.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1582-4934
DOI:10.1111/jcmm.70693