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Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.

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Title: Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.
Authors: Sauter KA; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America., Webb GM; Division of Pathobiology and Immunology, ONPRC, Hillsboro, Oregon, United States of America., Bader L; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America., Kreklywich CN; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, Oregon, United States of America., Takahashi DL; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America., Zaro C; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America., McGuire CM; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America., Lewis AD; Division of Comparative Medicine, ONPRC, Hillsboro, Oregon, United States of America., Colgin LMA; Division of Comparative Medicine, ONPRC, Hillsboro, Oregon, United States of America., Kirigiti MA; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America., Blomenkamp H; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America., Pessoa C; Division of Pathobiology and Immunology, ONPRC, Hillsboro, Oregon, United States of America., Humkey M; Division of Pathobiology and Immunology, ONPRC, Hillsboro, Oregon, United States of America., Hulahan J; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Sleeman M; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Zweig RC; Division of Comparative Medicine, ONPRC, Hillsboro, Oregon, United States of America., Thomas S; Division of Neuroscience, ONPRC, Hillsboro, Oregon, United States of America., Thomas A; Division of Neuroscience, ONPRC, Hillsboro, Oregon, United States of America., Gao L; Knight Cancer Institute, OHSU, Portland, Oregon, United States of America., Hirsch AJ; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, Oregon, United States of America., Levy M; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Cherry S; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Kahn SE; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, VA Puget Sound Health Care System and University of Washington, Seattle, Washington, United States of America., Slifka MK; Division of Neuroscience, ONPRC, Hillsboro, Oregon, United States of America., Streblow DN; Division of Pathobiology and Immunology, ONPRC, Hillsboro, Oregon, United States of America.; Vaccine and Gene Therapy Institute, Oregon Health and Science University (OHSU), Beaverton, Oregon, United States of America., Sacha JB; Division of Pathobiology and Immunology, ONPRC, Hillsboro, Oregon, United States of America., Kievit P; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America., Roberts CT; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America.; Division of Reproductive and Developmental Sciences, ONPRC., Hillsboro, Oregon, United States of America.
Source: PLoS pathogens [PLoS Pathog] 2025 Jul 24; Vol. 21 (7), pp. e1012988. Date of Electronic Publication: 2025 Jul 24 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
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  Data: Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates.
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Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22McGuire+CM%22">McGuire CM</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Lewis+AD%22">Lewis AD</searchLink>; Division of Comparative Medicine, ONPRC, Hillsboro, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Colgin+LMA%22">Colgin LMA</searchLink>; Division of Comparative Medicine, ONPRC, Hillsboro, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Kirigiti+MA%22">Kirigiti MA</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Blomenkamp+H%22">Blomenkamp H</searchLink>; Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Pessoa+C%22">Pessoa C</searchLink>; 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Division of Metabolic Health and Disease, Oregon National Primate Research Center (ONPRC), Beaverton, Oregon, United States of America.; Division of Reproductive and Developmental Sciences, ONPRC., Hillsboro, Oregon, United States of America.
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