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Multi-omic derived cell-type specific Alzheimer disease polygenic risk scores.

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Title: Multi-omic derived cell-type specific Alzheimer disease polygenic risk scores.
Authors: O'Neill N; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Kurniansyah N; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Zhu C; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Olayinka OA; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Mayeux R; Department of Neurology, Columbia University School of Medicine, New York, NY, USA., Haines JL; Cleveland Institute for Computational Biology, Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Pericak-Vance MA; John P. Hussman Institute for Human Genomics, Miller School of Medicine, Miami, FL, USA., Wang LS; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Farrer LA; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Departments of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Departments of Ophthalmology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA; Departments of Epidemiology, Boston University School of Public Health, Boston, MA, USA. Electronic address: farrer@bu.edu., Zhang X; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA. Electronic address: zhangxl@bu.edu.
Source: Neurobiology of aging [Neurobiol Aging] 2025 Nov; Vol. 155, pp. 44-52. Date of Electronic Publication: 2025 Jul 16.
Publication Type: Journal Article; Research Support, N.I.H., Intramural
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1497 (Electronic) Linking ISSN: 01974580 NLM ISO Abbreviation: Neurobiol Aging Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multi-omic derived cell-type specific Alzheimer disease polygenic risk scores.
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  Data: <searchLink fieldCode="AU" term="%22O'Neill+N%22">O'Neill N</searchLink>; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kurniansyah+N%22">Kurniansyah N</searchLink>; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+C%22">Zhu C</searchLink>; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Olayinka+OA%22">Olayinka OA</searchLink>; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mayeux+R%22">Mayeux R</searchLink>; Department of Neurology, Columbia University School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Haines+JL%22">Haines JL</searchLink>; Cleveland Institute for Computational Biology, Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Pericak-Vance+MA%22">Pericak-Vance MA</searchLink>; John P. Hussman Institute for Human Genomics, Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wang+LS%22">Wang LS</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schellenberg+GD%22">Schellenberg GD</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Farrer+LA%22">Farrer LA</searchLink>; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Departments of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Departments of Ophthalmology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA; Departments of Epidemiology, Boston University School of Public Health, Boston, MA, USA. Electronic address: farrer@bu.edu.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Bioinformatics Program, Boston University, Boston, MA, USA; Departments of Medicine (Section of Biomedical Genetics), Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA; Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA. Electronic address: zhangxl@bu.edu.
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  Data: <searchLink fieldCode="JN" term="%228100437%22">Neurobiology of aging</searchLink> [Neurobiol Aging] 2025 Nov; Vol. 155, pp. 44-52. <i>Date of Electronic Publication: </i>2025 Jul 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8100437 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-1497 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201974580%22">01974580 </searchLink><i>NLM ISO Abbreviation: </i>Neurobiol Aging <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.neurobiolaging.2025.07.009
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              Text: 2025 Nov
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