A cannabinoid receptor 1 inverse agonist induces weight loss and reduces airway hyperresponsiveness in a mouse model of obese asthma.
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| Title: | A cannabinoid receptor 1 inverse agonist induces weight loss and reduces airway hyperresponsiveness in a mouse model of obese asthma. |
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| Authors: | Morris CR; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Chandrasekaran R; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Butzirus IM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Daphtary N; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Aliyeva M; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Manuel AM; Mass Spectrometry and Proteomics Core, The University of Utah, Salt Lake City, Utah, United States., Tharp WG; Department of Anesthesiology, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Bates JHT; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Anathy V; Department of Pathology and Laboratory Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Poynter ME; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States., Duan J; Inversago Pharma Inc., Montreal, Quebec, Canada., Gaucher G; Inversago Pharma Inc., Montreal, Quebec, Canada., Crater GD; Inversago Pharma Inc., Montreal, Quebec, Canada., Dixon AE; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Vermont, Larner College of Medicine, Burlington, Vermont, United States. |
| Source: | American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2025 Sep 01; Vol. 329 (3), pp. L327-L340. Date of Electronic Publication: 2025 Jul 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1504 (Electronic) Linking ISSN: 10400605 NLM ISO Abbreviation: Am J Physiol Lung Cell Mol Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1522-1504 |
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| DOI: | 10.1152/ajplung.00049.2025 |