Self-driving microscopy detects the onset of protein aggregation and enables intelligent Brillouin imaging.

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Title: Self-driving microscopy detects the onset of protein aggregation and enables intelligent Brillouin imaging.
Authors: Ibrahim KA; Laboratory of Nanoscale Biology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. khalid.mohie@gmail.com.; Laboratory of Molecular and Chemical Biology of Neurodegeneration, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. khalid.mohie@gmail.com.; NCCR Bio-Inspired Materials, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. khalid.mohie@gmail.com., Cathala C; Laboratory of Nanoscale Biology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Bevilacqua C; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Feletti L; Laboratory of Nanoscale Biology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; NCCR Bio-Inspired Materials, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Prevedel R; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; German Center for Lung Research (DZL), Heidelberg, Germany., Lashuel HA; Laboratory of Molecular and Chemical Biology of Neurodegeneration, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. hilal.lashuel@epfl.ch., Radenovic A; Laboratory of Nanoscale Biology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. aleksandra.radenovic@epfl.ch.; NCCR Bio-Inspired Materials, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. aleksandra.radenovic@epfl.ch.
Source: Nature communications [Nat Commun] 2025 Jul 24; Vol. 16 (1), pp. 6699. Date of Electronic Publication: 2025 Jul 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-60912-0