Unraveling Cathepsin S regulation in interleukin-7-mediated anti-tumor immunity reveals its targeting potential against oral cancer.
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| Title: | Unraveling Cathepsin S regulation in interleukin-7-mediated anti-tumor immunity reveals its targeting potential against oral cancer. |
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| Authors: | Chang YC; TMU Research Center of Cancer Translational Medicine; Taipei Cancer Center, College of Medicine, Taipei Medical University Hospital, Taipei Medical University, No. 250, Wuxing Street, Taipei, 11031, Taiwan.; National Institute of Cancer Research, National Health Research Institutes, 367 Sheng-Li Road, Tainan, 70456, Taiwan.; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli, Taiwan., Chen SJ; Department of Oncology, Neurosurgery, Albert Einstein College of Medicine, New York, NY, USA., Chen SH; National Institute of Cancer Research, National Health Research Institutes, 367 Sheng-Li Road, Tainan, 70456, Taiwan.; Department of Oncology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan., Hsiao SY; Division of Hematology-Oncology, Department of Internal Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan.; Department of Nursing, Chung Hwa University of Medical Technology, Tainan, Taiwan., Chen LH; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; University Center for Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan., Chen CH; National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan., Liu CC; National Institute of Cancer Research, National Health Research Institutes, 367 Sheng-Li Road, Tainan, 70456, Taiwan., Chen YW; National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan., Liu KJ; National Institute of Cancer Research, National Health Research Institutes, 367 Sheng-Li Road, Tainan, 70456, Taiwan., Wu SY; Department of Oncology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan., Chu JM; National Institute of Cancer Research, National Health Research Institutes, 367 Sheng-Li Road, Tainan, 70456, Taiwan., Qiu LY; National Institute of Cancer Research, National Health Research Institutes, 367 Sheng-Li Road, Tainan, 70456, Taiwan., Chiang WF; Department of Oral and Maxillofacial Surgery, Chi Mei Medical Center, Liouying, Tainan, Taiwan.; School of Dentistry, National Yang Ming University, Taipei, Taiwan., Hsieh HP; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli, Taiwan.; Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan., Hsueh WY; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli, Taiwan.; Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan., Hsiao JR; Department of Otolaryngology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan., Shen MR; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Institue of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Obstetrics and Gynecology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan., Chang JY; TMU Research Center of Cancer Translational Medicine; Taipei Cancer Center, College of Medicine, Taipei Medical University Hospital, Taipei Medical University, No. 250, Wuxing Street, Taipei, 11031, Taiwan. jychang@tmu.edu.tw.; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli, Taiwan. jychang@tmu.edu.tw., Chang KY; National Institute of Cancer Research, National Health Research Institutes, 367 Sheng-Li Road, Tainan, 70456, Taiwan. kwang2@nhri.edu.tw.; Department of Oncology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan. kwang2@nhri.edu.tw.; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan. kwang2@nhri.edu.tw. |
| Source: | Journal of biomedical science [J Biomed Sci] 2025 Jul 24; Vol. 32 (1), pp. 69. Date of Electronic Publication: 2025 Jul 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127 (Electronic) Linking ISSN: 10217770 NLM ISO Abbreviation: J Biomed Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1423-0127 |
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| DOI: | 10.1186/s12929-025-01154-6 |
