Hepatocyte reporter cells and integrated metabolomic and transcriptomic analyses reveal insights into hepatocyte changes in offspring of pregnancies with obesity.
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| Title: | Hepatocyte reporter cells and integrated metabolomic and transcriptomic analyses reveal insights into hepatocyte changes in offspring of pregnancies with obesity. |
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| Authors: | Kozlovich SY; Department of Pediatrics, Division of Neonatology, Medical College of Wisconsin, 999 N. 92 Street, PO Box 1997, Milwaukee, WI, 53226, USA., Pan AY; Department of Pediatrics, Division of Bioinformatics and Quantitative Child Health, Medical College of Wisconsin, Milwaukee, WI, USA.; Center for Microbiome Research, Medical College of Wisconsin, Milwaukee, WI, USA., McIntosh JJ; Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Palatnik A; Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Jia S; Department of Pediatrics, Division of Endocrinology, Medical College of Wisconsin, Milwaukee, WI, USA., Hessner MJ; Center for Microbiome Research, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Pediatrics, Division of Endocrinology, Medical College of Wisconsin, Milwaukee, WI, USA., Nghiem-Rao TH; Department of Pediatrics, Division of Neonatology, Medical College of Wisconsin, 999 N. 92 Street, PO Box 1997, Milwaukee, WI, 53226, USA. hnghiem@mcw.edu. |
| Source: | Scientific reports [Sci Rep] 2025 Jul 25; Vol. 15 (1), pp. 27041. Date of Electronic Publication: 2025 Jul 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-10808-2 |
