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Mild psoriasis as a suitable model for proof-of-mechanism in a phase 1B setting: Results from a double-blind placebo-controlled trial with guselkumab.

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Bibliographic Details
Title: Mild psoriasis as a suitable model for proof-of-mechanism in a phase 1B setting: Results from a double-blind placebo-controlled trial with guselkumab.
Authors: Rousel J; Centre for Human Drug Research, Leiden, the Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Bergmans ME; Centre for Human Drug Research, Leiden, the Netherlands., Bruijnincx LJ; Centre for Human Drug Research, Leiden, the Netherlands., Lin S; Centre for Human Drug Research, Leiden, the Netherlands., der Kolk TN; Centre for Human Drug Research, Leiden, the Netherlands., Bohoslavsky R; Centre for Human Drug Research, Leiden, the Netherlands., Yavuz Y; Centre for Human Drug Research, Leiden, the Netherlands., Klarenbeek NB; Centre for Human Drug Research, Leiden, the Netherlands., Bouwstra JA; Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Rissmann R; Centre for Human Drug Research, Leiden, the Netherlands.; Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.; Leiden University Medical Centre, Leiden, the Netherlands., van Doorn MBA; Centre for Human Drug Research, Leiden, the Netherlands.; Erasmus Medical Centre, Rotterdam, the Netherlands.
Corporate Authors: Next‐Generation ImmunoDermatology Consortium (NGID)
Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Dec; Vol. 91 (12), pp. 3378-3388. Date of Electronic Publication: 2025 Jul 28.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1365-2125
DOI:10.1002/bcp.70179