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From spheroids to organoids: next-generation models for CAR-T cell therapy research in solid tumors.

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Title: From spheroids to organoids: next-generation models for CAR-T cell therapy research in solid tumors.
Authors: Jassin M; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium., Block A; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Department of Hematology, University Hospital of Liege, Liege, Belgium., Désiront L; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium., Vrancken L; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Department of Hematology, University Hospital of Liege, Liege, Belgium., Grégoire C; Department of Hematology, University Hospital of Liege, Liege, Belgium., Baron F; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Department of Hematology, University Hospital of Liege, Liege, Belgium., Ehx G; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Walloon Excellence in Life Sciences and Biotechnology (WELBIO) Department, Walloon Excellenxe in Life Research Institute, Wavre, Belgium., Nguyen TT; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium., Caers J; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Department of Hematology, University Hospital of Liege, Liege, Belgium.
Source: Frontiers in immunology [Front Immunol] 2025 Jul 11; Vol. 16, pp. 1626369. Date of Electronic Publication: 2025 Jul 11 (Print Publication: 2025).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: From spheroids to organoids: next-generation models for CAR-T cell therapy research in solid tumors.
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  Data: <searchLink fieldCode="AU" term="%22Jassin+M%22">Jassin M</searchLink>; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Block+A%22">Block A</searchLink>; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Department of Hematology, University Hospital of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Désiront+L%22">Désiront L</searchLink>; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Vrancken+L%22">Vrancken L</searchLink>; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Department of Hematology, University Hospital of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Grégoire+C%22">Grégoire C</searchLink>; Department of Hematology, University Hospital of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Baron+F%22">Baron F</searchLink>; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Department of Hematology, University Hospital of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Ehx+G%22">Ehx G</searchLink>; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Walloon Excellence in Life Sciences and Biotechnology (WELBIO) Department, Walloon Excellenxe in Life Research Institute, Wavre, Belgium.<br /><searchLink fieldCode="AU" term="%22Nguyen+TT%22">Nguyen TT</searchLink>; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.<br /><searchLink fieldCode="AU" term="%22Caers+J%22">Caers J</searchLink>; Laboratory of Hematology, Interdisciplinary Cluster for Applied Genoproteomics Institute (GIGA) Institute, University of Liege, Liege, Belgium.; Department of Hematology, University Hospital of Liege, Liege, Belgium.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2025 Jul 11; Vol. 16, pp. 1626369. <i>Date of Electronic Publication: </i>2025 Jul 11 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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              Text: 2025 Jul 11
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