A Phase 2 Randomized Trial of NBI-1065846 (TAK-041) in Patients With Anhedonia Associated With Major Depressive Disorder: Results of the TERPSIS Study.

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Title: A Phase 2 Randomized Trial of NBI-1065846 (TAK-041) in Patients With Anhedonia Associated With Major Depressive Disorder: Results of the TERPSIS Study.
Authors: Benedetto SR; Neurocrine Biosciences Inc., San Diego, CA., Ionescu A; Neurocrine Biosciences Inc., San Diego, CA., Ge T; Neurocrine Biosciences Inc., San Diego, CA., Furey M; Neurocrine Biosciences Inc., San Diego, CA., Lin S; Neurocrine Biosciences Inc., San Diego, CA., Jha MK; Department of Psychiatry and Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, TX., Krystal A; Department of Psychiatry, University of California, San Francisco, San Francisco, CA., Shah AA; Department of Psychiatry, Baylor College of Medicine, Houston, TX., Walling DP; CenExel CNS, Garden Grove, CA., Shah N; Neurocrine Biosciences Inc., San Diego, CA., Rizvi SJ; ASR Suicide and Depression Studies Program, St. Michael's Hospital, Toronto, Canada., Kennedy S; ASR Suicide and Depression Studies Program, St. Michael's Hospital, Toronto, Canada.; Department of Psychiatry, University of Toronto, Toronto, Canada., Laurenza A; Takeda Pharmaceutical Company Limited, Cambridge, MA., Murthy V; Takeda Pharmaceutical Company Limited, Cambridge, MA., Roberts E; Neurocrine Biosciences Inc., San Diego, CA., Singh JB; Neurocrine Biosciences Inc., San Diego, CA.
Source: Journal of clinical psychopharmacology [J Clin Psychopharmacol] 2025 Sep-Oct 01; Vol. 45 (5), pp. 432-440. Date of Electronic Publication: 2025 Jul 28.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Williams And Wilkins Country of Publication: United States NLM ID: 8109496 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-712X (Electronic) Linking ISSN: 02710749 NLM ISO Abbreviation: J Clin Psychopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1533-712X
DOI:10.1097/JCP.0000000000002046