Azaindole 1, a selective Rock1/2 kinase inhibitor, induces G2/M arrest and cell death in B-cell acute lymphoblastic leukemia (B-ALL).

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Title: Azaindole 1, a selective Rock1/2 kinase inhibitor, induces G2/M arrest and cell death in B-cell acute lymphoblastic leukemia (B-ALL).
Authors: Podgorica M; Department of Immunology, Oslo University Hospital, and KG Jebsen Center for B-cell Malignancies, Institute of Clinical Medicine, University of Oslo, and Oslo University Hospital, Norway.; Precision Immunotherapy Alliance (PRIMA), University of Oslo, Norway., Drivet E; Department of Immunology, Oslo University Hospital, and KG Jebsen Center for B-cell Malignancies, Institute of Clinical Medicine, University of Oslo, and Oslo University Hospital, Norway.; Precision Immunotherapy Alliance (PRIMA), University of Oslo, Norway., Vestbøstad J; Department of Immunology, Oslo University Hospital, and KG Jebsen Center for B-cell Malignancies, Institute of Clinical Medicine, University of Oslo, and Oslo University Hospital, Norway.; Precision Immunotherapy Alliance (PRIMA), University of Oslo, Norway., Kvam AK; Department of Haematology, Oslo University Hospital, Norway., Wik HS; Department of Haematology, Oslo University Hospital, Norway., Munthe L; Department of Immunology, Oslo University Hospital, and KG Jebsen Center for B-cell Malignancies, Institute of Clinical Medicine, University of Oslo, and Oslo University Hospital, Norway.; Precision Immunotherapy Alliance (PRIMA), University of Oslo, Norway., Schjerven H; Department of Immunology, Oslo University Hospital, and KG Jebsen Center for B-cell Malignancies, Institute of Clinical Medicine, University of Oslo, and Oslo University Hospital, Norway.; Department of Laboratory Medicine, University of California San Francisco, USA.
Source: Leukemia & lymphoma [Leuk Lymphoma] 2025 Dec; Vol. 66 (12), pp. 2311-2315. Date of Electronic Publication: 2025 Jul 29.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2403 (Electronic) Linking ISSN: 10268022 NLM ISO Abbreviation: Leuk Lymphoma Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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Description
ISSN:1029-2403
DOI:10.1080/10428194.2025.2536125