Non-mutated human tau stimulates Alzheimer's disease-relevant neurodegeneration in a microglia-dependent manner.

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Bibliographic Details
Title: Non-mutated human tau stimulates Alzheimer's disease-relevant neurodegeneration in a microglia-dependent manner.
Authors: Roy ER; Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA. Ethan.R.Roy@uth.tmc.edu.; University of Texas Health Science Center at Houston, 77030, Houston, TX, USA. Ethan.R.Roy@uth.tmc.edu., Wang Q; Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Huang K; McWilliams School of Biomedical Informatics at UTHealth Houston, Houston, TX, USA., Li S; Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Fan Y; Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Escobar E; Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Atkins CL; Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Huang S; Department of Diagnostic & Interventional Imaging, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Herrera JJ; Department of Diagnostic & Interventional Imaging, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Li W; Department of Biochemistry and Molecular Biology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Pridans C; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK., Zhou X; McWilliams School of Biomedical Informatics at UTHealth Houston, Houston, TX, USA., Ju C; Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Cao W; Department of Anesthesiology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA. Wei.Cao@uth.tmc.edu.; University of Texas Health Science Center at Houston, 77030, Houston, TX, USA. Wei.Cao@uth.tmc.edu.
Source: Scientific reports [Sci Rep] 2025 Jul 29; Vol. 15 (1), pp. 27664. Date of Electronic Publication: 2025 Jul 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-025-12869-9