Modulation of immunoglobulin G oligomerization by variable domain glycans: A mechanism to regulate complement activation.

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Title: Modulation of immunoglobulin G oligomerization by variable domain glycans: A mechanism to regulate complement activation.
Authors: Biersteker R; Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Abendstein L; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., van de Bovenkamp S; Department of Immunology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., van Dooren HJ; Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Hamers SMWR; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Kwekkeboom JC; Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Stork EM; Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Drijfhout JW; Department of Immunology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Rispens T; Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, 1066 CX Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, 1105 AZ, 1081 HV Amsterdam, The Netherlands., Koeleman CAM; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Trouw LA; Department of Immunology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Sharp TH; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.; School of Biochemistry, University of Bristol, Bristol BS8 1TD, United Kingdom., Toes REM; Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands., Kissel T; Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Source: PNAS nexus [PNAS Nexus] 2025 Jul 16; Vol. 4 (7), pp. pgaf216. Date of Electronic Publication: 2025 Jul 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press on behalf of the National Academy of Sciences Country of Publication: England NLM ID: 9918367777906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2752-6542 (Electronic) Linking ISSN: 27526542 NLM ISO Abbreviation: PNAS Nexus Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2752-6542
DOI:10.1093/pnasnexus/pgaf216