The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake.

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Title: The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake.
Authors: Stavrou-Dowd ZT; Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK., Parsons G; Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.; Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle Upon Tyne, NE2 4HH, UK., Rose C; Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK., Brown F; Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.; UK Health Security Agency, Porton, Salisbury, SP4 0JG, UK., Lees RS; Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK., Acosta-Serrano Á; Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK. aacosta3@nd.edu.; Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, 46556, USA. aacosta3@nd.edu., Haines LR; Department of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK. lhaines@nd.edu.; Department of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, 46556, USA. lhaines@nd.edu.
Source: Parasites & vectors [Parasit Vectors] 2025 Jul 31; Vol. 18 (1), pp. 316. Date of Electronic Publication: 2025 Jul 31.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305 (Electronic) Linking ISSN: 17563305 NLM ISO Abbreviation: Parasit Vectors Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1756-3305
DOI:10.1186/s13071-025-06939-0