Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.
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| Title: | Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis. |
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| Authors: | Davis SH; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Mathieson M; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Buchanan KI; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Dawson A; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Smith A; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Cocco M; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Tamaki FK; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Post JM; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Baragaña B; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Jansen C; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Kiczun M; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Zuccotto F; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Wood G; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Scullion P; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Ray PC; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Epemolu O; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Lopez-Román EM; Global Health Medicines R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760 Madrid, Spain., López LG; Global Health Medicines R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760 Madrid, Spain., Engelhart CA; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States., Kim J; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States., Pino PA; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States., Schnappinger D; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States., Read KD; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Encinas L; Global Health Medicines R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760 Madrid, Spain., Bates RH; Global Health Medicines R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760 Madrid, Spain., Wyatt PG; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Green SR; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K., Cleghorn LAT; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, DD1 5EH Dundee, U.K. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2025 Aug 14; Vol. 68 (15), pp. 16459-16482. Date of Electronic Publication: 2025 Aug 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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