Differential DNA methylation patterns in whole blood from ACPA-positive patients with DMARD-naïve rheumatoid arthritis at clinical disease onset.

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Title: Differential DNA methylation patterns in whole blood from ACPA-positive patients with DMARD-naïve rheumatoid arthritis at clinical disease onset.
Authors: Svendsen AJ; Research Unit for Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Internal Medicine & Emergency, Odense University Hospital, Svendborg, Denmark., Mengel-From J; Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Junker P; Department of Rheumatology, Odense University Hospital, Odense, Denmark., Dalgård C; Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense, Denmark., Davey Smith G; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Relton CL; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Elliott HR; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Kyvik K; Research Unit of Clinical Genetics, University of Southern Denmark, Odense, Denmark., Lindegaard H; Department of Rheumatology, Odense University Hospital, Odense, Denmark., Christensen AF; Department of Internal Medicine, Lillebaelt Hospital, Kolding, Denmark., Tan Q; Research Unit for Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Unit of Human Genetics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Source: Frontiers in immunology [Front Immunol] 2025 Jul 21; Vol. 16, pp. 1488161. Date of Electronic Publication: 2025 Jul 21 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1488161