Preclinical evaluation of [68Ga]Ga-AAZTA-FAPI-46: a novel PET tracer for targeting fibroblast activation protein (FAP).

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Title: Preclinical evaluation of [68Ga]Ga-AAZTA-FAPI-46: a novel PET tracer for targeting fibroblast activation protein (FAP).
Authors: Rizzo R; Center for Biotechnology and Translational Medicine, University of Turin, Piazza Nizza 44/bis, Turin, 10126, Italy., Rainone P; Nuclear Medicine and PET Cyclotron Unit, IRCCS Ospedale San Raffaele, Milano, Italy.; Institute of Molecular Bioimaging and Physiology-IBFM, CNR, Segrate, Italy., Stefania R; DISIT, University of Eastern Piedmont, Viale Teresa Michel 11, Alessandria, 15121, Italy., Belloli S; Nuclear Medicine and PET Cyclotron Unit, IRCCS Ospedale San Raffaele, Milano, Italy.; Institute of Molecular Bioimaging and Physiology-IBFM, CNR, Segrate, Italy., Valtorta S; Nuclear Medicine and PET Cyclotron Unit, IRCCS Ospedale San Raffaele, Milano, Italy.; Institute of Molecular Bioimaging and Physiology-IBFM, CNR, Segrate, Italy., Coliva A; Nuclear Medicine and PET Cyclotron Unit, IRCCS Ospedale San Raffaele, Milano, Italy., Maspero M; Nuclear Medicine and PET Cyclotron Unit, IRCCS Ospedale San Raffaele, Milano, Italy., Avalle L; DISIT, University of Eastern Piedmont, Viale Teresa Michel 11, Alessandria, 15121, Italy., Capozza M; Center for Biotechnology and Translational Medicine, University of Turin, Piazza Nizza 44/bis, Turin, 10126, Italy., Moresco RM; Nuclear Medicine and PET Cyclotron Unit, IRCCS Ospedale San Raffaele, Milano, Italy.; Institute of Molecular Bioimaging and Physiology-IBFM, CNR, Segrate, Italy., D'Alessandria C; Department of Nuclear Medicine, TUM University Hospital rechts der Isar, 81675, Munich, Germany., Terreno E; Center for Biotechnology and Translational Medicine, University of Turin, Piazza Nizza 44/bis, Turin, 10126, Italy. enzo.terreno@unito.it.
Source: EJNMMI radiopharmacy and chemistry [EJNMMI Radiopharm Chem] 2025 Aug 05; Vol. 10 (1), pp. 51. Date of Electronic Publication: 2025 Aug 05.
Publication Type: Journal Article
Journal Info: Publisher: Springer Open Country of Publication: England NLM ID: 101714628 Publication Model: Electronic Cited Medium: Internet ISSN: 2365-421X (Electronic) Linking ISSN: 2365421X NLM ISO Abbreviation: EJNMMI Radiopharm Chem Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2365-421X
DOI:10.1186/s41181-025-00375-2