Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP.
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| Title: | Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP. |
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| Authors: | Batra S; School of Biosciences, Division of Microbiology, Brewing and Biotechnology, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.; Interdisciplinary Biomedical Research Center, School of Science and Technology, Nottingham Trent University, Nottingham, UK., Olmo F; Department of Parasitology, Faculty of Sciences, University of Granada, Granada, Spain., Ragan TJ; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK., Kaplan M; Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK., Calvaresi V; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK., Frank AM; Department of Immunology and Microbiology, Centre for Medical Parasitology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lancey C; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK., Assadipapari M; Advanced Optics & Photonics Laboratory, Department of Engineering, School of Science & Technology, Nottingham Trent University, Nottingham, UK., Ying C; Advanced Optics & Photonics Laboratory, Department of Engineering, School of Science & Technology, Nottingham Trent University, Nottingham, UK., Struwe WB; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK., Hesketh EL; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK., Kelly JM; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK., Barfod L; Department of Immunology and Microbiology, Centre for Medical Parasitology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Campeotto I; School of Biosciences, Division of Microbiology, Brewing and Biotechnology, University of Nottingham, Sutton Bonington Campus, Loughborough, UK. ivan.campeotto@nottingham.ac.uk. |
| Source: | Nature communications [Nat Commun] 2025 Aug 05; Vol. 16 (1), pp. 7164. Date of Electronic Publication: 2025 Aug 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-62068-3 |
