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Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP.

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Title: Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP.
Authors: Batra S; School of Biosciences, Division of Microbiology, Brewing and Biotechnology, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.; Interdisciplinary Biomedical Research Center, School of Science and Technology, Nottingham Trent University, Nottingham, UK., Olmo F; Department of Parasitology, Faculty of Sciences, University of Granada, Granada, Spain., Ragan TJ; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK., Kaplan M; Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK., Calvaresi V; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK., Frank AM; Department of Immunology and Microbiology, Centre for Medical Parasitology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lancey C; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK., Assadipapari M; Advanced Optics & Photonics Laboratory, Department of Engineering, School of Science & Technology, Nottingham Trent University, Nottingham, UK., Ying C; Advanced Optics & Photonics Laboratory, Department of Engineering, School of Science & Technology, Nottingham Trent University, Nottingham, UK., Struwe WB; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK., Hesketh EL; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK., Kelly JM; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK., Barfod L; Department of Immunology and Microbiology, Centre for Medical Parasitology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Campeotto I; School of Biosciences, Division of Microbiology, Brewing and Biotechnology, University of Nottingham, Sutton Bonington Campus, Loughborough, UK. ivan.campeotto@nottingham.ac.uk.
Source: Nature communications [Nat Commun] 2025 Aug 05; Vol. 16 (1), pp. 7164. Date of Electronic Publication: 2025 Aug 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP.
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  Data: <searchLink fieldCode="AU" term="%22Batra+S%22">Batra S</searchLink>; School of Biosciences, Division of Microbiology, Brewing and Biotechnology, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.; Interdisciplinary Biomedical Research Center, School of Science and Technology, Nottingham Trent University, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Olmo+F%22">Olmo F</searchLink>; Department of Parasitology, Faculty of Sciences, University of Granada, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Ragan+TJ%22">Ragan TJ</searchLink>; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Kaplan+M%22">Kaplan M</searchLink>; Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Calvaresi+V%22">Calvaresi V</searchLink>; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Frank+AM%22">Frank AM</searchLink>; Department of Immunology and Microbiology, Centre for Medical Parasitology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lancey+C%22">Lancey C</searchLink>; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Assadipapari+M%22">Assadipapari M</searchLink>; Advanced Optics & Photonics Laboratory, Department of Engineering, School of Science & Technology, Nottingham Trent University, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Ying+C%22">Ying C</searchLink>; Advanced Optics & Photonics Laboratory, Department of Engineering, School of Science & Technology, Nottingham Trent University, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Struwe+WB%22">Struwe WB</searchLink>; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hesketh+EL%22">Hesketh EL</searchLink>; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Kelly+JM%22">Kelly JM</searchLink>; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Barfod+L%22">Barfod L</searchLink>; Department of Immunology and Microbiology, Centre for Medical Parasitology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Campeotto+I%22">Campeotto I</searchLink>; School of Biosciences, Division of Microbiology, Brewing and Biotechnology, University of Nottingham, Sutton Bonington Campus, Loughborough, UK. ivan.campeotto@nottingham.ac.uk.
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