High-dimensional single-cell phenotyping unveils persistent differences in immune cell profiles between severe and moderate seasonal influenza.

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Title: High-dimensional single-cell phenotyping unveils persistent differences in immune cell profiles between severe and moderate seasonal influenza.
Authors: Bodin J; Section of Immunology, Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway., Tunheim G; Section of Immunology, Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway., Kristoffersen AB; Section of Immunology, Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway., Herstad TK; Section of Immunology, Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway., Vianello E; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Haks MC; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., van Veen S; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Wæhre T; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway., Kran AB; Division of Infection Control, Department of Infectious Disease Registries, Norwegian Institute of Public Health, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Lartey SL; Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway., Zhou F; Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway., Cox RJ; Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Microbiology, Haukeland University Hospital, Bergen, Norway., Ottenhoff THM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands., Dyrhol-Riise AM; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Nygaard UC; Section of Immunology, Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway., Oftung F; Section of Immunology, Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway., Mjaaland S; Section of Immunology, Department of Method Development and Analytics, Norwegian Institute of Public Health, Oslo, Norway.
Source: Frontiers in immunology [Front Immunol] 2025 Jul 22; Vol. 16, pp. 1576861. Date of Electronic Publication: 2025 Jul 22 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1576861