IRX3 controls a SUMOylation-dependent differentiation switch in adipocyte precursor cells.
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| Title: | IRX3 controls a SUMOylation-dependent differentiation switch in adipocyte precursor cells. |
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| Authors: | Bjune JI; Mohn Research Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway.; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway., Laber S; Medical Research Council Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire, UK., Lawrence-Archer L; Mohn Research Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway., Nothnagel PMC; Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo, Blindern, Oslo, Norway., Yamada S; Center of Translational Oral Research-Tissue engineering, Department of Clinical Dentistry, University of Bergen, Bergen, Norway., Zhao X; Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo, Blindern, Oslo, Norway., Panahandeh Strømland P; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway., Al-Sharabi N; Center of Translational Oral Research-Tissue engineering, Department of Clinical Dentistry, University of Bergen, Bergen, Norway., Mustafa K; Center of Translational Oral Research-Tissue engineering, Department of Clinical Dentistry, University of Bergen, Bergen, Norway., Njølstad PR; Mohn Research Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Pediatrics and Adolescents, Haukeland University Hospital, Bergen, Norway., Claussnitzer M; Mohn Research Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Cox RD; Medical Research Council Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Oxfordshire, UK., Chymkowitch P; Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo, Blindern, Oslo, Norway. pierre.chymkowitch@ibv.uio.no., Mellgren G; Mohn Research Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway. gunnar.mellgren@uib.no.; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway. gunnar.mellgren@uib.no.; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway. gunnar.mellgren@uib.no., Dankel SN; Mohn Research Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway. simon.dankel@uib.no.; Mohn Nutrition Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway. simon.dankel@uib.no.; Hormone Laboratory, Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway. simon.dankel@uib.no. |
| Source: | Nature communications [Nat Commun] 2025 Aug 06; Vol. 16 (1), pp. 7248. Date of Electronic Publication: 2025 Aug 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-62361-1 |
