Potassium binding by carbonyl clusters, halophilic adaptation and catalysis of Haloferax mediterranei D-2-hydroxyacid dehydrogenase.

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Title: Potassium binding by carbonyl clusters, halophilic adaptation and catalysis of Haloferax mediterranei D-2-hydroxyacid dehydrogenase.
Authors: Domenech J; Dept. Bioquımica y Biología Molecular y EQA. Universidad de Alicante, Alicante, Spain., Pramanpol N; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.; National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani, Thailand., Bisson C; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.; Evotec (UK) Ltd, Dorothy Crowfoot Hodgkin Campus 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire, UK., Sedelnikova SE; School of Biosciences, University of Sheffield, Sheffield, United Kingdom., Barrett JR; School of Biosciences, University of Sheffield, Sheffield, United Kingdom., Dakhil AAAB; School of Biosciences, University of Sheffield, Sheffield, United Kingdom., Mykhaylyk V; Diamond Light Source, Harwell Campus, Didcot, United Kingdom., Abdelhameed AS; National Centre for Macromolecular Hydrodynamics, School of Biosciences, University of Nottingham, College Road, Sutton Bonington, Nottingham, UK.; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia., Harding SE; National Centre for Macromolecular Hydrodynamics, School of Biosciences, University of Nottingham, College Road, Sutton Bonington, Nottingham, UK., Rice DW; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.; Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia., Baker PJ; School of Biosciences, University of Sheffield, Sheffield, United Kingdom. p.baker@sheffield.ac.uk., Ferrer J; Dept. Bioquımica y Biología Molecular y EQA. Universidad de Alicante, Alicante, Spain. JFerrer@ua.es.
Source: Communications biology [Commun Biol] 2025 Aug 06; Vol. 8 (1), pp. 1170. Date of Electronic Publication: 2025 Aug 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
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  Data: Potassium binding by carbonyl clusters, halophilic adaptation and catalysis of Haloferax mediterranei D-2-hydroxyacid dehydrogenase.
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  Data: <searchLink fieldCode="AU" term="%22Domenech+J%22">Domenech J</searchLink>; Dept. Bioquımica y Biología Molecular y EQA. Universidad de Alicante, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Pramanpol+N%22">Pramanpol N</searchLink>; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.; National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathum Thani, Thailand.<br /><searchLink fieldCode="AU" term="%22Bisson+C%22">Bisson C</searchLink>; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.; Evotec (UK) Ltd, Dorothy Crowfoot Hodgkin Campus 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire, UK.<br /><searchLink fieldCode="AU" term="%22Sedelnikova+SE%22">Sedelnikova SE</searchLink>; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Barrett+JR%22">Barrett JR</searchLink>; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dakhil+AAAB%22">Dakhil AAAB</searchLink>; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mykhaylyk+V%22">Mykhaylyk V</searchLink>; Diamond Light Source, Harwell Campus, Didcot, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Abdelhameed+AS%22">Abdelhameed AS</searchLink>; National Centre for Macromolecular Hydrodynamics, School of Biosciences, University of Nottingham, College Road, Sutton Bonington, Nottingham, UK.; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Harding+SE%22">Harding SE</searchLink>; National Centre for Macromolecular Hydrodynamics, School of Biosciences, University of Nottingham, College Road, Sutton Bonington, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Rice+DW%22">Rice DW</searchLink>; School of Biosciences, University of Sheffield, Sheffield, United Kingdom.; Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia.<br /><searchLink fieldCode="AU" term="%22Baker+PJ%22">Baker PJ</searchLink>; School of Biosciences, University of Sheffield, Sheffield, United Kingdom. p.baker@sheffield.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ferrer+J%22">Ferrer J</searchLink>; Dept. Bioquımica y Biología Molecular y EQA. Universidad de Alicante, Alicante, Spain. JFerrer@ua.es.
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  Data: <searchLink fieldCode="JN" term="%22101719179%22">Communications biology</searchLink> [Commun Biol] 2025 Aug 06; Vol. 8 (1), pp. 1170. <i>Date of Electronic Publication: </i>2025 Aug 06.
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