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Sulfoxide-diazirine (SODA) as a Cleavable Photoaffinity Group To Enable the Identification of Photolabeled Modification Sites via LC-MS3.

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Title: Sulfoxide-diazirine (SODA) as a Cleavable Photoaffinity Group To Enable the Identification of Photolabeled Modification Sites via LC-MS3.
Authors: Chen S; AG Chemical Proteomics, Leibniz Institute for Analytical Sciences─ISAS, Otto-Hahn-Str. 6b, 44227 Dortmund, Germany., Sanner MF; Center for Computational Structural Biology, The Scripps Research Institute, La Jolla, San Diego 92037, California, United States., Gracias Leone DL; Laboratory of Chemical Biology, Department of Cellular and Molecular Medicine, KU Leuven─University of Leuven, Herestraat 49, Box 802, 3000 Leuven, Belgium., Loroch S; Medizinisches Proteom-Center, Ruhr-Universität Bochum, Building ProDi E2.240, Gesundheitscampus 4, D-44801 Bochum, Germany.; QC-MS, Fa. Dr. Loroch, BioMedizin Zentrum, Otto-Hahn-Straße 15, 44149 Dortmund, Germany., Forli S; Center for Computational Structural Biology, The Scripps Research Institute, La Jolla, San Diego 92037, California, United States., Verhelst SHL; AG Chemical Proteomics, Leibniz Institute for Analytical Sciences─ISAS, Otto-Hahn-Str. 6b, 44227 Dortmund, Germany.; Laboratory of Chemical Biology, Department of Cellular and Molecular Medicine, KU Leuven─University of Leuven, Herestraat 49, Box 802, 3000 Leuven, Belgium.
Source: Analytical chemistry [Anal Chem] 2025 Aug 19; Vol. 97 (32), pp. 17512-17520. Date of Electronic Publication: 2025 Aug 06.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-6882
DOI:10.1021/acs.analchem.5c02409