Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in rats.

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Title: Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in rats.
Authors: Martin L; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA.; Department of Anesthesiology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Stratton HJ; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Salih LY; Department of Pharmacology and Physiology, School of Medicine, Saint Louis University, St. Louis, MO, USA., Dumaire N; Department of Pharmacology and Physiology, School of Medicine, Saint Louis University, St. Louis, MO, USA., Gomez K; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Do LD; French Reference Center for Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS-UCBL-CNRS UMR 5284-INSERM U1314, Université Claude Bernard Lyon 1, Lyon, France., Loya-Lopez S; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Tang C; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Calderon-Rivera A; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Ran D; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Nunna V; Department of Pharmacology and Physiology, School of Medicine, Saint Louis University, St. Louis, MO, USA., Bellampalli SS; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., François-Moutal L; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA.; Department of Pharmacology and Physiology, School of Medicine, Saint Louis University, St. Louis, MO, USA., Luo S; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Porreca F; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Ibrahim M; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA.; Department of Anesthesiology, College of Medicine, The University of Arizona, Tucson, AZ, USA., Rogemond V; French Reference Center for Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS-UCBL-CNRS UMR 5284-INSERM U1314, Université Claude Bernard Lyon 1, Lyon, France., Honnorat J; French Reference Center for Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS-UCBL-CNRS UMR 5284-INSERM U1314, Université Claude Bernard Lyon 1, Lyon, France., Khanna R; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA.; Department of Pharmacology & Therapeutics and Pain and Center for Advanced Pain Therapeutics and Research (CAPTOR), College of Medicine, University of Florida, Gainesville, FL, USA., Moutal A; Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA. aubin.moutal@health.slu.edu.; Department of Pharmacology and Physiology, School of Medicine, Saint Louis University, St. Louis, MO, USA. aubin.moutal@health.slu.edu.
Source: Nature communications [Nat Commun] 2025 Aug 07; Vol. 16 (1), pp. 7311. Date of Electronic Publication: 2025 Aug 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-62380-y