Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device.
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| Title: | Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device. |
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| Authors: | Otomo A; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan., Nishijima K; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan., Murakami Y; Department of Mechanical Engineering, Tokai University School of Engineering, Hiratsuka, Kanagawa, Japan., Ishikawa M; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science, Fujita Health University, Aichi, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Yudahira H; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan., Shimakura K; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan., Okano H; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science, Fujita Health University, Aichi, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Aoki M; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan., Kimura H; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan.; Department of Mechanical Engineering, Tokai University School of Engineering, Hiratsuka, Kanagawa, Japan., Hadano S; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan. |
| Source: | Frontiers in cellular neuroscience [Front Cell Neurosci] 2025 Jul 24; Vol. 19, pp. 1590732. Date of Electronic Publication: 2025 Jul 24 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477935 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5102 (Print) Linking ISSN: 16625102 NLM ISO Abbreviation: Front Cell Neurosci Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1662-5102 |
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| DOI: | 10.3389/fncel.2025.1590732 |
