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Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device.

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Title: Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device.
Authors: Otomo A; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan., Nishijima K; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan., Murakami Y; Department of Mechanical Engineering, Tokai University School of Engineering, Hiratsuka, Kanagawa, Japan., Ishikawa M; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science, Fujita Health University, Aichi, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Yudahira H; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan., Shimakura K; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan., Okano H; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science, Fujita Health University, Aichi, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Aoki M; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan., Kimura H; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan.; Department of Mechanical Engineering, Tokai University School of Engineering, Hiratsuka, Kanagawa, Japan., Hadano S; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan.
Source: Frontiers in cellular neuroscience [Front Cell Neurosci] 2025 Jul 24; Vol. 19, pp. 1590732. Date of Electronic Publication: 2025 Jul 24 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477935 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5102 (Print) Linking ISSN: 16625102 NLM ISO Abbreviation: Front Cell Neurosci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device.
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  Data: <searchLink fieldCode="AU" term="%22Otomo+A%22">Otomo A</searchLink>; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Nishijima+K%22">Nishijima K</searchLink>; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Murakami+Y%22">Murakami Y</searchLink>; Department of Mechanical Engineering, Tokai University School of Engineering, Hiratsuka, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Ishikawa+M%22">Ishikawa M</searchLink>; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science, Fujita Health University, Aichi, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yudahira+H%22">Yudahira H</searchLink>; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Shimakura+K%22">Shimakura K</searchLink>; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Okano+H%22">Okano H</searchLink>; Division of CNS Regeneration and Drug Discovery, International Center for Brain Science, Fujita Health University, Aichi, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Aoki+M%22">Aoki M</searchLink>; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan.<br /><searchLink fieldCode="AU" term="%22Kimura+H%22">Kimura H</searchLink>; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan.; Department of Mechanical Engineering, Tokai University School of Engineering, Hiratsuka, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Hadano+S%22">Hadano S</searchLink>; Molecular Neuropathobiology Laboratory, Department of Physiology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101477935%22">Frontiers in cellular neuroscience</searchLink> [Front Cell Neurosci] 2025 Jul 24; Vol. 19, pp. 1590732. <i>Date of Electronic Publication: </i>2025 Jul 24 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101477935 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1662-5102 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216625102%22">16625102 </searchLink><i>NLM ISO Abbreviation: </i>Front Cell Neurosci <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Jul 24
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