SETD2 drives METTL14-mediated m6A to suppress Piezo1 Attenuation and activate TGM2 to promote pulmonary hypertension.

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Title: SETD2 drives METTL14-mediated m6A to suppress Piezo1 Attenuation and activate TGM2 to promote pulmonary hypertension.
Authors: Zhao SS; Department of Cardiovascular Surgery, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, China., Yuan C; Department of Cardiovascular Surgery, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, China., Liu JL; Institute of Translational Medicine, Shanghai University, Shanghai, 200444, China., Wu QC; Department of Cardiovascular Surgery, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, China. ndyfy00619@ncu.edu.cn., Zhou XL; Department of Cardiovascular Surgery, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, China. zhouxliang@ncu.edu.cn.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Aug 08; Vol. 82 (1), pp. 302. Date of Electronic Publication: 2025 Aug 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-9071
DOI:10.1007/s00018-025-05809-3