Human mitochondrial CYP2E1-mediated styrene metabolism increases oxidative stress and impairs antioxidant rescue in Caenorhabditis elegans.
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| Title: | Human mitochondrial CYP2E1-mediated styrene metabolism increases oxidative stress and impairs antioxidant rescue in Caenorhabditis elegans. |
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| Authors: | Ameyaa-Sakyi A; Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON K1S 5B6, Canada., Harris TR; Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON K1S 5B6, Canada., Clarke CE; Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON K1S 5B6, Canada., McMullin DR; Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON K1S 5B6, Canada., Gordon KL; Department of Biology, University of North Carolina, Chapel Hill, NC, USA., Sherwood D; Department of Biology, Duke University, Durham, NC 27708, United States., Hartman JH; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA., Rand AA; Department of Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON K1S 5B6, Canada. Electronic address: amy.rand@carleton.ca. |
| Source: | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2025 Dec; Vol. 298, pp. 110319. Date of Electronic Publication: 2025 Aug 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 100959500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-0456 (Print) Linking ISSN: 15320456 NLM ISO Abbreviation: Comp Biochem Physiol C Toxicol Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1532-0456 |
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| DOI: | 10.1016/j.cbpc.2025.110319 |
