A randomized trial to evaluate the pharmacokinetics, pharmacodynamics, and safety of vadadustat in patients with anemia associated with chronic kidney disease receiving hemodialysis.

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Title: A randomized trial to evaluate the pharmacokinetics, pharmacodynamics, and safety of vadadustat in patients with anemia associated with chronic kidney disease receiving hemodialysis.
Authors: Navarro-Gonzales P; Akebia Therapeutics, Inc, 245 1st St, Cambridge, MA, 02142, USA., Chavan A; Akebia Therapeutics, Inc, 245 1st St, Cambridge, MA, 02142, USA., Wang D; Akebia Therapeutics, Inc, 245 1st St, Cambridge, MA, 02142, USA., Burke SK; Akebia Therapeutics, Inc, 245 1st St, Cambridge, MA, 02142, USA., Dykstra K; Akebia Therapeutics, Inc, 245 1st St, Cambridge, MA, 02142, USA. kdykstra@Akebia.com.
Source: BMC nephrology [BMC Nephrol] 2025 Aug 11; Vol. 26 (1), pp. 453. Date of Electronic Publication: 2025 Aug 11.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967793 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2369 (Electronic) Linking ISSN: 14712369 NLM ISO Abbreviation: BMC Nephrol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1471-2369
DOI:10.1186/s12882-025-04367-x