Thymine DNA Glycosylase Binds to R-Loops and Excises 5-Formyl and 5-Carboxyl Cytosine from DNA/RNA Hybrids.

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Title: Thymine DNA Glycosylase Binds to R-Loops and Excises 5-Formyl and 5-Carboxyl Cytosine from DNA/RNA Hybrids.
Authors: Zhu B; Department of Chemistry, Texas A&M University, College Station, Texas, 77843, USA., Pidugu LS; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Cook ME; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Nie XY; Department of Biology, Center For Biological Clock Research, Texas A&M University, College Station, TX 77843, USA., Amarasekara EAPT; Department of Chemistry, Texas A&M University, College Station, Texas, 77843, USA., Menet JS; Department of Biology, Center For Biological Clock Research, Texas A&M University, College Station, TX 77843, USA., Drohat AC; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Sczepanski JT; Department of Chemistry, Texas A&M University, College Station, Texas, 77843, USA.; Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, 77843, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 05. Date of Electronic Publication: 2025 Aug 05.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.08.05.668694