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Protective effect of pirfenidone against ovarian ischemia/reperfusion injury in rats via modulation of TLR4/p38 MAPK/IL-1β and HIF-1α/VEGF-A signaling pathways.

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Title: Protective effect of pirfenidone against ovarian ischemia/reperfusion injury in rats via modulation of TLR4/p38 MAPK/IL-1β and HIF-1α/VEGF-A signaling pathways.
Authors: Abdel-Aziz AM; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61511, Egypt., Hassan M; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61511, Egypt., Thabit DM; Department of Pathology, Faculty of Medicine, Minia University, Minia 61511, Egypt., Said S; Department of Microbiology and Immunology, Faculty of Medicine, Minia University, Minia 61511, Egypt., Shawky HA; Department of Human Anatomy and Embryology, Faculty of Medicine, Minia University, Minia 61511, Egypt., Elsayed SH; Department of Medical Biochemistry, Faculty of Medicine, Minia University, Minia 61511, Egypt., Khalaf HM; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61511, Egypt.
Source: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2025 Oct 30; Vol. 77 (11), pp. 1583-1592.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print Cited Medium: Internet ISSN: 2042-7158 (Electronic) Linking ISSN: 00223573 NLM ISO Abbreviation: J Pharm Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Protective effect of pirfenidone against ovarian ischemia/reperfusion injury in rats via modulation of TLR4/p38 MAPK/IL-1β and HIF-1α/VEGF-A signaling pathways.
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  Data: <searchLink fieldCode="JN" term="%220376363%22">The Journal of pharmacy and pharmacology</searchLink> [J Pharm Pharmacol] 2025 Oct 30; Vol. 77 (11), pp. 1583-1592.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0376363 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2042-7158 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223573%22">00223573 </searchLink><i>NLM ISO Abbreviation: </i>J Pharm Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1093/jpp/rgaf066
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              Text: 2025 Oct 30
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