Safety and Efficacy of the NMDA-2b-Selective Negative Allosteric Modulator BI 1569912: A Phase Ib Randomized Trial in Major Depressive Disorder.
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| Title: | Safety and Efficacy of the NMDA-2b-Selective Negative Allosteric Modulator BI 1569912: A Phase Ib Randomized Trial in Major Depressive Disorder. |
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| Authors: | McIntyre RS; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada., Sanacora G; Yale University, New Haven, Connecticut, USA., Walling DP; CenExel CNS, Garden Grove, California, USA., Cohen EA; CenExel Hassman Research Institute, Marlton, New Jersey, USA., Malhotra S; Neuro-Behavioral Clinical Research, Canton, Ohio, USA., Rosenbrock H; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany., Schmitz M; mainanalytics GmbH, Sulzbach/Taunus, Germany., Scholz A; Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany., Süssmuth SD; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany., De Crescenzo F; Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany. |
| Source: | Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Nov; Vol. 118 (5), pp. 1202-1212. Date of Electronic Publication: 2025 Aug 14. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I; Multicenter Study |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1532-6535 |
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| DOI: | 10.1002/cpt.70018 |
