Chemical vs Physical Radioenhancement from TiO2 and Au Nanoparticles to Overcome Hypoxic Radioresistance in X-ray Therapy.

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Title: Chemical vs Physical Radioenhancement from TiO2 and Au Nanoparticles to Overcome Hypoxic Radioresistance in X-ray Therapy.
Authors: Gerken LRH; Nanomaterials in Health Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland., Schaller LGS; Nanomaterials in Health Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland., Nißler R; Nanomaterials in Health Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland.; Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland.; The Ingenuity Lab, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland., Habermann S; Nanomaterials in Health Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland.; Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland., Beckers C; Laboratory for Applied Radiobiology, Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland., Dommke M; Fraunhofer IKTS, Fraunhofer Institute for Ceramic Technologies and Systems, Michael-Faraday-Straße 1, Hermsdorf 07629, Germany.; Institute of Technical and Environmental Chemistry, Friedrich Schiller University Jena, Philosophenweg 7a, Jena 07743, Germany., Heinze S; Department of Radiation Oncology, Cantonal Hospital St. Gallen (KSSG), Rorschacherstrasse 95, CH-9007 St. Gallen, Switzerland., Pruschy M; Laboratory for Applied Radiobiology, Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland., Plasswilm L; Department of Radiation Oncology, Cantonal Hospital St. Gallen (KSSG), Rorschacherstrasse 95, CH-9007 St. Gallen, Switzerland.; Department of Radiation Oncology, Inselspital University Hospital, 3010 Bern, Switzerland., Herrmann IK; Nanomaterials in Health Laboratory, Department of Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland.; Nanoparticle Systems Engineering Laboratory, Institute of Energy and Process Engineering (IEPE), Department of Mechanical and Process Engineering (D-MAVT), ETH Zurich, Sonneggstrasse 3, 8092 Zurich, Switzerland.; The Ingenuity Lab, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland.; Faculty of Medicine, University of Zurich, Rämistrasse 71, 8006 Zurich, Switzerland.
Source: Nano letters [Nano Lett] 2025 Aug 27; Vol. 25 (34), pp. 12806-12815. Date of Electronic Publication: 2025 Aug 14.
Publication Type: Journal Article; Clinical Trial
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101088070 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6992 (Electronic) Linking ISSN: 15306984 NLM ISO Abbreviation: Nano Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1530-6992
DOI:10.1021/acs.nanolett.5c02080