Activated Protein C Suppresses Cardiomyocyte Senescence in Diabetic Cardiomyopathy via PAR1/PAR3-P85-CaMKIIδ Axis.
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| Title: | Activated Protein C Suppresses Cardiomyocyte Senescence in Diabetic Cardiomyopathy via PAR1/PAR3-P85-CaMKIIδ Axis. |
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| Authors: | Zhang Y; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Dai L; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Wang M; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Zhong X; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Liu X; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Zhang K; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Luo L; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Wang L; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Dong W; Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China., Vaczy A; Department of Sports Biology and Kinesiology, Faculty of Sciences, University of Pécs, Pécs, Hungary.; ELKH-PTE PACAP Research Team, Department of Anatomy, Medical School, University of Pécs, Pécs, Hungary., Li L; Department of Sports Biology and Kinesiology, Faculty of Sciences, University of Pécs, Pécs, Hungary.; ELKH-PTE PACAP Research Team, Department of Anatomy, Medical School, University of Pécs, Pécs, Hungary., Atlasz T; Department of Sports Biology and Kinesiology, Faculty of Sciences, University of Pécs, Pécs, Hungary.; ELKH-PTE PACAP Research Team, Department of Anatomy, Medical School, University of Pécs, Pécs, Hungary., Madhusudhan T; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany., Xu C; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China., Wang H; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China.; Department of Cardiology, Tongji Xianning Hospital, Xianning, Hubei, China., Zeng H; Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy, Wuhan, Hubei, China. |
| Source: | Diabetes [Diabetes] 2025 Oct 01; Vol. 74 (10), pp. 1802-1813. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1939-327X |
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| DOI: | 10.2337/db25-0077 |
