Challenging Traditional ADME Assumptions for Physiologically Based Pharmacokinetic Models for Intravenous Administration of Iron-Carbohydrate Nanomedicines: Potential Utility of Gold Nanoparticle Models as a Roadmap.
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| Title: | Challenging Traditional ADME Assumptions for Physiologically Based Pharmacokinetic Models for Intravenous Administration of Iron-Carbohydrate Nanomedicines: Potential Utility of Gold Nanoparticle Models as a Roadmap. |
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| Authors: | Alston AB; CSL Vifor, Flughofstrasse 61, 8152, Glattbrugg, Switzerland. amy.barton@viforpharma.com., Lin Z; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, FL, 32610, USA., Gustafson HH; Department of Pediatrics, Ben Towne Center for Childhood Cancer and Blood Disorders Research, University of Washington, Seattle, WA, 98101, USA., Flühmann B; CSL Vifor, Flughofstrasse 61, 8152, Glattbrugg, Switzerland., Digigow R; CSL Vifor, Flughofstrasse 61, 8152, Glattbrugg, Switzerland., Ayala-Nunez V; Nanomaterials in Health Laboratory, Empa - Swiss Federal Laboratories for Materials Science and Technology, St. Gallen, Switzerland., Schmidt S; Department of Pharmaceutics, Center for Pharmacometrics and Systems Pharmacology, College of Pharmacy, University of Florida, Orlando, FL, 32827, USA. |
| Source: | Clinical pharmacokinetics [Clin Pharmacokinet] 2025 Oct; Vol. 64 (10), pp. 1477-1494. Date of Electronic Publication: 2025 Aug 15. |
| Publication Type: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40815410 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Challenging Traditional ADME Assumptions for Physiologically Based Pharmacokinetic Models for Intravenous Administration of Iron-Carbohydrate Nanomedicines: Potential Utility of Gold Nanoparticle Models as a Roadmap. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Alston+AB%22">Alston AB</searchLink>; CSL Vifor, Flughofstrasse 61, 8152, Glattbrugg, Switzerland. amy.barton@viforpharma.com.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Gustafson+HH%22">Gustafson HH</searchLink>; Department of Pediatrics, Ben Towne Center for Childhood Cancer and Blood Disorders Research, University of Washington, Seattle, WA, 98101, USA.<br /><searchLink fieldCode="AU" term="%22Flühmann+B%22">Flühmann B</searchLink>; CSL Vifor, Flughofstrasse 61, 8152, Glattbrugg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Digigow+R%22">Digigow R</searchLink>; CSL Vifor, Flughofstrasse 61, 8152, Glattbrugg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ayala-Nunez+V%22">Ayala-Nunez V</searchLink>; Nanomaterials in Health Laboratory, Empa - Swiss Federal Laboratories for Materials Science and Technology, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schmidt+S%22">Schmidt S</searchLink>; Department of Pharmaceutics, Center for Pharmacometrics and Systems Pharmacology, College of Pharmacy, University of Florida, Orlando, FL, 32827, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227606849%22">Clinical pharmacokinetics</searchLink> [Clin Pharmacokinet] 2025 Oct; Vol. 64 (10), pp. 1477-1494. <i>Date of Electronic Publication: </i>2025 Aug 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Review; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22%22"> </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>7606849 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1926 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203125963%22">03125963 </searchLink><i>NLM ISO Abbreviation: </i>Clin Pharmacokinet <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40815410 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s40262-025-01561-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1477 Titles: – TitleFull: Challenging Traditional ADME Assumptions for Physiologically Based Pharmacokinetic Models for Intravenous Administration of Iron-Carbohydrate Nanomedicines: Potential Utility of Gold Nanoparticle Models as a Roadmap. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Alston AB – PersonEntity: Name: NameFull: Lin Z – PersonEntity: Name: NameFull: Gustafson HH – PersonEntity: Name: NameFull: Flühmann B – PersonEntity: Name: NameFull: Digigow R – PersonEntity: Name: NameFull: Ayala-Nunez V – PersonEntity: Name: NameFull: Schmidt S IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2025 Oct Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1179-1926 Numbering: – Type: volume Value: 64 – Type: issue Value: 10 Titles: – TitleFull: Clinical pharmacokinetics Type: main |
| ResultId | 1 |
