View in EDS

Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a.

Saved in:
Bibliographic Details
Title: Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a.
Authors: Burbidge O; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK., Pastok MW; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK., Papini D; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK., Hodder SL; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK., Zenkevičiūtė G; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK., Tan KZJ; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK., Turberville S; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK., Noble MEM; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK., Endicott JA; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK. Electronic address: jane.endicott@ncl.ac.uk., Itzhaki L; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK. Electronic address: lsi10@cam.ac.uk.
Source: Structure (London, England : 1993) [Structure] 2025 Nov 06; Vol. 33 (11), pp. 1984-1997.e12. Date of Electronic Publication: 2025 Aug 14.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40816278
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16<superscript>INK4a</superscript>.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Burbidge+O%22">Burbidge O</searchLink>; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Pastok+MW%22">Pastok MW</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Papini+D%22">Papini D</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Hodder+SL%22">Hodder SL</searchLink>; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Zenkevičiūtė+G%22">Zenkevičiūtė G</searchLink>; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Tan+KZJ%22">Tan KZJ</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Turberville+S%22">Turberville S</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Noble+MEM%22">Noble MEM</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Endicott+JA%22">Endicott JA</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, NE2 4HH Newcastle upon Tyne, UK. Electronic address: jane.endicott@ncl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Itzhaki+L%22">Itzhaki L</searchLink>; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK. Electronic address: lsi10@cam.ac.uk.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101087697%22">Structure (London, England : 1993)</searchLink> [Structure] 2025 Nov 06; Vol. 33 (11), pp. 1984-1997.e12. <i>Date of Electronic Publication: </i>2025 Aug 14.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101087697 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-4186 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209692126%22">09692126 </searchLink><i>NLM ISO Abbreviation: </i>Structure <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40816278
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.str.2025.07.017
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1984
    Titles:
      – TitleFull: Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Burbidge O
      – PersonEntity:
          Name:
            NameFull: Pastok MW
      – PersonEntity:
          Name:
            NameFull: Papini D
      – PersonEntity:
          Name:
            NameFull: Hodder SL
      – PersonEntity:
          Name:
            NameFull: Zenkevičiūtė G
      – PersonEntity:
          Name:
            NameFull: Tan KZJ
      – PersonEntity:
          Name:
            NameFull: Turberville S
      – PersonEntity:
          Name:
            NameFull: Noble MEM
      – PersonEntity:
          Name:
            NameFull: Endicott JA
      – PersonEntity:
          Name:
            NameFull: Itzhaki L
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 06
              M: 11
              Text: 2025 Nov 06
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1878-4186
          Numbering:
            – Type: volume
              Value: 33
            – Type: issue
              Value: 11
          Titles:
            – TitleFull: Structure (London, England : 1993)
              Type: main
ResultId 1