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Disrupted Calcium Dynamics in Reactive Astrocytes Occur with End Feet-Arteriole Decoupling in an Amyloid Mouse Model of Alzheimer's Disease.

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Title: Disrupted Calcium Dynamics in Reactive Astrocytes Occur with End Feet-Arteriole Decoupling in an Amyloid Mouse Model of Alzheimer's Disease.
Authors: Weiss BE; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536.; Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Gant JC; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Lin RL; Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Gollihue JL; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Rogers CB; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Kraner SD; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Rucker EB; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Katsumata Y; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536.; Department of Biostatistics, University of Kentucky, Lexington, Kentucky 40536., Jiang Y; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536.; Department of Behavioral Science, University of Kentucky, Lexington, Kentucky 40536., Nelson PT; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536.; Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Kentucky, Lexington, Kentucky 40536., Wilcock DM; Stark Neuroscience Research Institute, Indianapolis, Indiana 46202., Sompol P; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536.; Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Thibault O; Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, Kentucky 40536., Norris CM; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky 40536 cnorr2@uky.edu.; Department of Pharmacology and Nutritional Sciences, University of Kentucky College of Medicine, Lexington, Kentucky 40536.
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2025 Oct 01; Vol. 45 (40). Date of Electronic Publication: 2025 Oct 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1529-2401
DOI:10.1523/JNEUROSCI.0349-25.2025