Integrated Systems Biology Identifies Disruptions in Mitochondrial Function and Metabolism as Key Contributors to HFpEF.

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Bibliographic Details
Title: Integrated Systems Biology Identifies Disruptions in Mitochondrial Function and Metabolism as Key Contributors to HFpEF.
Authors: Gibb AA; Center for Cardiometabolic Science, Christina Lee Brown Envirome Institute, Department of Medicine, University of Louisville, Louisville, Kentucky, USA; Aging and Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., LaPenna K; Cardiovascular Center for Excellence, Department of Pharmacology, Louisiana State University Health Science Center, New Orleans, Louisiana, USA., Gaspar RB; Aging and Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Latchman NR; Aging and Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Tan Y; Fox Chase Cancer Center, Temple University, Philadelphia, Pennsylvania, USA., Choya-Foces C; Aging and Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Doiron JE; Cardiovascular Center for Excellence, Department of Pharmacology, Louisiana State University Health Science Center, New Orleans, Louisiana, USA., Li Z; Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Xia H; Cardiovascular Center for Excellence, Department of Pharmacology, Louisiana State University Health Science Center, New Orleans, Louisiana, USA., Lazaropoulos MP; Aging and Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Conwell M; Aging and Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Sharp TE 3rd; Department of Molecular Pharmacology and Physiology, University of South Florida Health, Tampa, Florida, USA., Goodchild TT; Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Lefer DJ; Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. Electronic address: david.lefer@cshs.org., Elrod JW; Aging and Cardiovascular Discovery Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA. Electronic address: elrod@temple.edu.
Source: JACC. Basic to translational science [JACC Basic Transl Sci] 2025 Sep; Vol. 10 (9), pp. 101334. Date of Electronic Publication: 2025 Aug 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier on behalf of the American College of Cardiology Foundation Country of Publication: United States NLM ID: 101677259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2452-302X (Electronic) Linking ISSN: 2452302X NLM ISO Abbreviation: JACC Basic Transl Sci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2452-302X
DOI:10.1016/j.jacbts.2025.101334