Computational ranking identifies Plexin-B2 in circulating tumor cell clustering with monocytes in breast cancer metastasis.

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Title: Computational ranking identifies Plexin-B2 in circulating tumor cell clustering with monocytes in breast cancer metastasis.
Authors: Schuster E; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Driskill Graduate Program in the Life Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Dashzeveg NK; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Tong F; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Jia Y; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., El-Shennawy L; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Zhang T; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Hoffman AD; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; ExoMira Medicine Inc, Chicago, IL, USA., Kitata RB; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Kibria G; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Zhang Y; Division of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Squires JR; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Zheng C; Center for Artificial Intelligence in Drug Discovery, Case Western Reserve University, Cleveland, OH, USA., Ramos E; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Taftaf R; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Scholten D; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Driskill Graduate Program in the Life Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Almubarak HF; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Driskill Graduate Program in the Life Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Adorno-Cruz V; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Sullivan DP; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Reduzzi C; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell School of Medicine, New York, NY, USA., Minor AC; Driskill Graduate Program in the Life Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Purev-Ochir W; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Spahija S; Division of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Xu R; Center for Artificial Intelligence in Drug Discovery, Case Western Reserve University, Cleveland, OH, USA., Siziopikou KP; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Platanias LC; Division of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Shah A; Division of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Muller WA; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Gradishar WJ; Division of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Cristofanilli M; Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell School of Medicine, New York, NY, USA., Tsai CF; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Shi T; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA. Tujin.Shi@pnnl.gov., Liu H; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. huiping.liu@northwestern.edu.; Division of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. huiping.liu@northwestern.edu.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. huiping.liu@northwestern.edu.; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. huiping.liu@northwestern.edu.; Chan Zuckerberg Biohub Chicago, Chicago, IL, USA. huiping.liu@northwestern.edu.
Source: Nature communications [Nat Commun] 2025 Aug 16; Vol. 16 (1), pp. 7649. Date of Electronic Publication: 2025 Aug 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Computational ranking identifies Plexin-B2 in circulating tumor cell clustering with monocytes in breast cancer metastasis.
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